A Different Type of Dementia Is Changing What’s Known About Cognitive Decline (Links to an external site)

Doctors told Ray Hester he was in the beginning stages of Alzheimer’s, but a brain scan revealed he had LATE dementia. “There’s a certain amount of relief knowing that it’s not Alzheimer’s,” his wife, Sandy, said.

A recently recognized form of dementia is changing the understanding of cognitive decline, improving the ability to diagnose patients and underscoring the need for a wider array of treatments. Patients are increasingly being diagnosed with the condition, known as LATE, and guidelines advising doctors how to identify it were published this year. LATE is now estimated to […]

Staff Spotlight Alyssa Hiserote

Alyssa Hiserote

Alyssa Hiserote earned her Bachelor of Science in Nursing from the University of Illinois at Chicago and later completed her Master of Science in Nursing at UIC as well. After five years of bedside nursing with a focus in pediatrics, she chose to pursue her passion for research and accepted a Research Nurse Coordinator position […]

Kannampallil, Wiley named medical informatics fellows (Links to an external site)

Kannampallil (left) and Wiley (right)

Thomas Kannampallil, PhD, chief data scientist and assistant dean for data science at WashU Medicine, and Laura Wiley, PhD, an associate professor of neurology at WashU Medicine, were named 2025 American College of Medical Informatics (ACMI) fellows. They were among 24 professionals from the United States and abroad recognized by peers for their ongoing contributions to […]

Seniors Abdelmoity, Karinshak were Rhodes Scholars finalists (Links to an external site)

Seniors Omar Abdelmoity (left) and Marilee Karinshak have both leveraged their talents as scientists and communicators to help underserved populations. (Photos: Joe Angeles/WashU)

Washington University in St. Louis seniors Omar Abdelmoity and Marilee Karinshak were finalists for the Rhodes Scholarship, one of the globe’s highest academic honors. Abdelmoity, of the Kansas City suburb of Overland Park, Kan., is majoring in biology in Arts & Sciences and was recently awarded the Goldwater Scholarship, a national award that honors young […]

Smith, Hiserote and Harshbarger announced as Neurology Staff Employees of the Quarter

Jill Smith, Alyssa Hiserote, AJ Harshbarger

The Department of Neurology congratulates three staff members for being awarded the Neurology Staff Employees of the Quarter for Q1 FY26. The department accepts nominations for three award categories to highlight the dedication and accomplishments of our staff members — clinical, research and administration. Clinical Staff Employee of the Quarter Jill Smith Research Nurse CoordinatorMovement […]

Video: Why one man with a genetic predisposition for Alzheimer’s disease is defying the odds (Links to an external site)

Medical professional cares for a elderly woman in a wheelchair

Nearly 7 million Americans currently live with Alzheimer’s and by 2060, experts say that number could be as high as 14 million. Scientists are trying to find out how one man has been able to stave off Alzheimer’s for 25 years, despite having a rare genetic mutation that, doctors say, essentially guaranteed he’d develop the […]

What if we can stop Alzheimer’s before it starts? (Links to an external site)

What if we could stop Alzheimer's before it starts?

Our focus is simple: stop Alzheimer’s before it starts. This disease steals the moments that make us who we are and the memories we share. That’s why we believe in attacking Alzheimer’s from every angle — because every breakthrough means more time, more hope and more moments together for families who can’t wait.

Resident Spotlight Brendan Whitelaw

Brendan Whitelaw

Brendan Whitelaw, MD, PhD, is a third year in the Adult Neurology Residency Program at Washington University School of Medicine in St. Louis. He is planning to specialize in vascular neurology and pursue a career as a physician scientist studying the molecular mechanisms driving cerebrovascular disease. Whitelaw went to college at the University of Pennsylvania, […]

Faculty Profile Sarah Biber

Sarah Biber

Sarah Biber, PhD, is an interdisciplinary researcher whose work integrates data science, bioinformatics, human-centered systems engineering, and implementation science. From 2021 to 2025, she co-led the National Alzheimer’s Coordinating Center (NACC) as Executive Director and multi-Principal Investigator (mPI), guiding its transformation into a modern multimodal cloud-based platform that integrates longitudinal clinical, imaging, neuropathological, biomarker, genomic […]

Alzheimer’s disrupts circadian rhythms of plaque-clearing brain cells (Links to an external site)

Illustration of a brain and a clock. One side has a starry night sky, the other has a blue sky with clouds.

Alzheimer’s disease is notorious for scrambling patients’ daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease. These symptoms suggest a link between the progression of the disease and the […]