Zooming in on a single disease and studying it intensely is often the most productive route to finding treatments. But there’s no easy way to distinguish among people living with any of the primary tauopathies — a group of rare brain diseases marked by rapidly worsening problems with thinking and movement — because the symptoms […]
ST. LOUIS — Joe knew something was terribly wrong when his wife, an energetic nurse and mother of three, became forgetful in her early 60s. Four years ago, Lynn was diagnosed with dementia but decided against having a spinal tap that would have shown whether the cause was Alzheimer’s disease.
Memory loss is often the first sign of Alzheimer’s disease, followed by confusion and difficulty thinking. These symptoms reflect the typical pattern of worsening damage to brain tissues. Toxic clusters of proteins first concentrate in the temporal lobes of the brain — the memory area — before spreading to parts of the brain important for […]
Alzheimer’s, Parkinson’s and many other neurodegenerative diseases are marked by damaging clusters of proteins in the brain. Scientists have expended enormous effort searching for ways to treat such conditions by clearing these toxic clusters but have had limited success.
An idea that has propelled Alzheimer’s research for more than 30 years is approaching its day of reckoning. Scientists are launching a study designed to make or break the hypothesis that Alzheimer’s is caused by a sticky substance called beta-amyloid. The study will give an experimental anti-amyloid drug to people as young as 18 who […]
Families that have a child with Rett syndrome, a rare neurological disorder that almost exclusively affects females, often travel hundreds of miles to the Rett Spectrum Clinic in St. Louis — a collaboration between Washington University School of Medicine and St. Louis Children’s Hospital — for multispecialty care and access to innovative clinical trials.
The Department of Neurology congratulates Neurology Medical Student Education Coordinator Chrissy McIntosh for being awarded the first-ever Neurology Staff Employee of the Quarter for Q1 FY23. McIntosh was nominated by faculty and staff for her work in managing the extensive transition of the department’s clerkship program to the Medical School’s new Gateway curriculum. Those who […]
Four faculty members at Washington University School of Medicine in St. Louis have been elected to the National Academy of Medicine, a part of the National Academy of Sciences. They are Opeolu M. Adeoye, MD; Farshid Guilak, PhD; David H. Gutmann, MD, PhD; and Jonathan Kipnis, PhD. Membership in the academy is considered one of the […]
Scientists have identified a handful of gene mutations that cause or contribute to the onset of Alzheimer’s disease. But many scientists suspect that other DNA changes may help drive Alzheimer’s-related damage to brain cells and lead to symptoms of confusion and memory loss experienced by patients.
When the COVID-19 pandemic struck in the spring of 2022, students and staff at schools that serve children with intellectual and developmental disabilities (IDD) were left stranded. These students and staff faced unique circumstances because they could not always follow the CDC guidance on masking, testing, and social distancing due to the nature of these […]