Genes linked to Alzheimer’s disease risk in APOE4 carriers identified

An international team of Alzheimer’s researchers led by Michael E. Belloy, PhD, assistant professor of neurology and of psychiatry at WashU Medicine, pooled data from multiple genetics databases and public repositories to conduct a large-scale analysis of individuals of European, African and Japanese ancestries. Their findings, published in Alzheimer’s & Dementia: The Journal of the […]

Bateman and Holtzman receive 2026 Dean’s Medal for Excellence in Innovation & Commercialization

Randall J. Bateman, MD, the Charles F. & Joanne Knight Distinguished Professor of Neurology, and David M. Holtzman, MD, the Barbara Burton and Reuben M. Morriss III Distinguished Professor, have been selected as joint recipients of the 2026 WashU Medicine Dean’s Medal for Excellence in Innovation & Commercialization. This award recognizes WashU Medicine faculty members […]

Shellhaas installed as David T. Blasingame Professor

Renée Shellhaas, MD, MS, was installed as the David T. Blasingame Professor on Monday, June 8. The ceremony included remarks from David H. Perlmutter, MD, executive vice chancellor for medical affairs and the George and Carol Bauer Dean of Washington University School of Medicine in St. Louis, and Jin-Moo Lee, MD, PhD, head of the […]

Three new genetic modifiers connected to risk factors in Alzheimer’s disease

Image showing the three chromosomal locations identified in this study on a graph.

Autosomal dominant Alzheimer’s disease (ADAD) is a form of genetically inherited Alzheimer’s that makes up only about 1% of Alzheimer’s disease occurrences. However, because of the extremely high rate and early age at which individuals with the gene mutations develop Alzheimer’s disease, and also because of the high heritability of the mutation, ADAD is widely […]

New comprehensive data platform could transform how Alzheimer’s disease is studied and treated

With an increasingly aging global population and no available preventative treatments, Alzheimer’s disease and related dementias are poised to become an even larger public health challenge. The mechanisms underlying Alzheimer’s disease are difficult to study because the disease has a long developmental period during which changes in the brain can occur years before symptoms appear. […]

Aravamuthan and Saligrama celebrated for first NIH R01 grants

On April 8, Washington University School of Medicine in St. Louis recognized investigators who received their first R01 research grants from the National Institutes of Health (NIH). Receiving an R01 grant is an important milestone for scientists who are establishing their careers as independent researchers. Bhooma R. Aravamuthan, MD, DPhil, FAAN, FCNS, assistant professor of […]

Eleven Faculty and Staff Selected to Receive 2026 AAN Awards

Headshots of the eleven AAN award winners listed in the article.

Eleven members of the Department of Neurology have been selected as 2026 award recipients by the American Academy of Neurology (AAN) in recognition of their accomplishments in education, research, or service. The AAN is the world’s largest professional organization in the fields of neurology and neurosciences and publishes several high-impact journals including the flagship journal […]

Carpenter and Bucelli Recognized for Clinical Excellence with Neville Grant Award

images of David A. Carpenter, MD, and Robert C. Bucelli, MD, PhD, in white lab coats

David A. Carpenter, MD, and Robert C. Bucelli, MD, PhD, will join the select group of physicians who have received the Dr. Neville Grant Award for Clinical Excellence. The award is administered by the Barnes-Jewish Hospital Medical Staff Association in honor of the late Dr. Neville Grant, who passed away in 2009. The Neville Grant […]

Study Reports Successful Results in First Anti-Amyloid Treatment of HIV+ Individual

PET scan images demonstrating absence of amyloid in a patient with HIV cognitive impairment contrasting with image confirming aggregated amyloid in reported patient with Alzheimer Disease.

A new case report published by David B. Clifford, MD, and colleagues detailed the anti-amyloid therapy treatment course of a patient who developed Alzheimer’s disease concurrently with a pre-existing HIV diagnosis. The patient, who was diagnosed with HIV in 2005, began showing signs of cognitive decline in 2015 and received a clinical diagnosis of Alzheimer’s […]