Labs by research area
Holtzman Lab
David Holtzman, MD
Leading research into the mechanisms of neurodegeneration, with a focus on Alzheimer’s disease. Through studies on proteins like apoE and tau, and factors such as sleep, immune response and neuronal activity, the lab aims to uncover pathways that drive disease progression and identify targets for therapy.
Hyrc Lab
Krzysztof Hyrc, PhD
Studies ionic mechanisms of excitotoxic neuronal cell death. Using optical techniques and low affinity calcium indicators, the lab investigates intracellular ion concentrations to better understand how neurons respond to injury and stress.
Ju Lab
Yo-El Ju, MD, MSCI
Investigating how sleep and circadian rhythms influence neurodegenerative diseases. Through translational and clinical research, the lab aims to identify and treat sleep dysfunction to reduce disease burden, improve quality of life and promote healthy aging.
Kotzbauer Lab
Paul Kotzbauer, MD, PhD
Advances research on neurodegenerative diseases, focusing on Parkinson’s disease and infantile neuroaxonal dystrophy. The lab investigates alpha-synuclein aggregation, neuronal connectivity and enzyme dysfunction to develop imaging tools and treatments that slow disease progression and improve diagnosis.
Kress Lab
Geraldine Kress, PhD
Studing how the circadian system affects cognitive function during aging and Alzheimer’s disease. By investigating changes in brain physiology and behavior, the lab aims to uncover mechanisms that drive disease progression and identify strategies to improve outcomes and promote healthy aging.
Kummer Lab
Terrance T. Kummer, MD, PhD
Investigating cellular damage in traumatic brain injury and Alzheimer’s disease. With a focus on synaptic and gray matter injury, the lab uses innovative imaging techniques like SEQUIN to quantify synapse loss and explore its connection to neurodegeneration.
Lee Lab
Jin-Moo Lee, MD, PhD
Investigating how the brain heals after injury, focusing on stroke, Alzheimer’s disease and cerebral small vessel disease. Using molecular biology, neuroimaging and genomics, the lab bridges basic science and clinical care to develop therapies that promote recovery and repair.
Li Lab
Mingjie Li, MD, PhD
Developing viral vectors to improve gene delivery to neural cells for research and treatment of neurological disorders. Focusing on lentiviral and adeno-associated virus systems, the lab supports neuroscience studies by creating tools for cell culture and in vivo experiments that target disease mechanisms and therapeutic strategies.
Ly Lab
Cindy Ly, MD, PhD
Investigates the molecular mechanisms of amyotrophic lateral sclerosis and related neuromuscular disorders, aiming to translate genetic discoveries into targeted therapies.
Mar Lab
Soe Mar, MD
Leading research focused on pediatric multiple sclerosis, white matter diseases and pediatric migraine. Her work also extends internationally to HIV-related neurocognitive disorders and neuroinfectious diseases, aiming to improve diagnosis and care for children affected by complex neurological conditions.