Morris Lab

John Carl Morris, MD

The focus of John Morris’ research and practice is Alzheimer’s disease and other neurological disorders associated with aging. Specific research interests include improving the diagnosis of early-stage Alzheimer’s disease, clinicopathological correlations in dementing disorders, evaluating new drugs for the treatment of dementia, establishing phenotypes for inherited forms of Alzheimer’s disease and other dementias and identifying preclinical stages of Alzheimer’s disease by biomarker and neuroimaging studies.

Principal investigator

John Morris, MD

John Morris, MD

Harvey A. & Dorismae Hacker Friedman Professor of Neurology
Director, Section of Aging & Dementia
Professor, Pathology and Immunology
Director, Center for Aging
Director, Memory and Aging Project


  Morris lab

 
Top areas of adult care: Alzheimer’s disease, dementia, geriatric neurology

Research profile
Clinical profile

Recent publications

  • Gene-SGAN: discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering
    Gene-SGAN: discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clusteringYang, Z., Wen, J., Abdulkadir, A., Cui, Y., Erus, G., Mamourian, E., Melhem, R., Srinivasan, D., Govindarajan, S. T., Chen, J., Habes, M., Masters, C. L., Maruff, P., Fripp, J., Ferrucci, L., Albert, M. S., Johnson, S. C., Morris, J. C., LaMontagne, P., Marcus, D. S., & 8 othersBenzinger, T. L. S., Wolk, D. A., Shen, L., Bao, J., Resnick, S. M., Shou, H., Nasrallah, I. M. & Davatzikos, C., Dec 2024, In: Nature communications. 15, 1, 354.Research output: Contribution to journal › Article › peer-review
  • Predictors and outcomes of fluctuations in the clinical dementia rating scale
    Predictors and outcomes of fluctuations in the clinical dementia rating scaleWilks, H., Benzinger, T. L. S., Schindler, S. E., Cruchaga, C., Morris, J. C. & Hassenstab, J., Mar 2024, In: Alzheimer's and Dementia. 20, 3, p. 2080-2088 9 p.Research output: Contribution to journal › Article › peer-review
  • Personality predictors of dementia diagnosis and neuropathological burden: An individual participant data meta-analysis
    Personality predictors of dementia diagnosis and neuropathological burden: An individual participant data meta-analysisBeck, E. D., Yoneda, T., James, B. D., Bennett, D. A., Hassenstab, J., Katz, M. J., Lipton, R. B., Morris, J., Mroczek, D. K. & Graham, E. K., Mar 2024, In: Alzheimer's and Dementia. 20, 3, p. 1497-1514 18 p.Research output: Contribution to journal › Article › peer-review
  • Relationships of Cognitive Measures with Cerebrospinal Fluid but Not Imaging Biomarkers of Alzheimer Disease Vary between Black and White Individuals
    Relationships of Cognitive Measures with Cerebrospinal Fluid but Not Imaging Biomarkers of Alzheimer Disease Vary between Black and White IndividualsBonomi, S., Lu, R., Schindler, S. E., Bui, Q., Lah, J. J., Wolk, D., Gleason, C. E., Sperling, R., Roberson, E. D., Levey, A. I., Shaw, L., Van Hulle, C., Benzinger, T., Adams, M., Manzanares, C., Qiu, D., Hassenstab, J., Moulder, K. L., Balls-Berry, J. E., Johnson, K., & 16 othersJohnson, S. C., Murchison, C. F., Luo, J., Gremminger, E., Agboola, F., Grant, E. A., Hornbeck, R., Massoumzadeh, P., Keefe, S., Dierker, D., Gray, J., Henson, R. L., Streitz, M., Mechanic-Hamilton, […]
  • Investigating White Matter Neuroinflammation in Alzheimer Disease Using Diffusion-Based Neuroinflammation Imaging
    Investigating White Matter Neuroinflammation in Alzheimer Disease Using Diffusion-Based Neuroinflammation ImagingWang, Q., Schindler, S. E., Chen, G., Mckay, N. S., McCullough, A., Flores, S., Liu, J., Sun, Z., Wang, S., Wang, W., Hassenstab, J., Cruchaga, C., Perrin, R. J., Fagan, A. M., Morris, J. C., Wang, Y. & Benzinger, T. L. S., Feb 1 2024, In: Neurology. 102, 4, p. e208013Research output: Contribution to journal › Article › peer-review
Complete bibliography