Morris Lab
John Carl Morris, MD
The focus of John Morris’ research and practice is Alzheimer’s disease and other neurological disorders associated with aging. Specific research interests include improving the diagnosis of early-stage Alzheimer’s disease, clinicopathological correlations in dementing disorders, evaluating new drugs for the treatment of dementia, establishing phenotypes for inherited forms of Alzheimer’s disease and other dementias and identifying preclinical stages of Alzheimer’s disease by biomarker and neuroimaging studies.
Principal investigator

John Morris, MD
Harvey A. & Dorismae Hacker Friedman Professor of Neurology
Director, Aging & Dementia
Professor, Pathology and Immunology
Director, Center for Aging
Director, Memory and Aging Project
- Phone: 314-286-1967
Top areas of adult care: Alzheimer’s disease, dementia, geriatric neurology
Recent publications
- Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer diseaseKnight Alzheimer Disease Research Center (Knight ADRC), the Dominantly Inherited Alzheimer Network (DIAN), Alzheimer’s Disease Neuroimaging Initiative (ADNI), ADNI-DOD, A4 Study Team, the Australian Imaging Biomarkers, Lifestyle (AIBL) Study, Ali, M., Archer, D. B., Gorijala, P., Western, D., Timsina, J., Fernández, M. V., Chen, G., Gordon, B., Benzinger, T. L. S., Xiong, C., Morris, J. C., Bateman, R. J., Karch, C. M., McDade, E., Sung, Y. J., & 1 othersCruchaga, C., Dec 2023, In: Acta Neuropathologica Communications. 11, 1, 68.Research output: Contribution to journal › Article › peer-review
- Neuropsychiatric Symptoms and Alzheimer Disease Biomarkers Independently Predict Progression to Incident Cognitive ImpairmentBabulal, G. M., Chen, L., Murphy, S. A., Doherty, J. M., Johnson, A. M. & Morris, J. C., Dec 2023, In: American Journal of Geriatric Psychiatry. 31, 12, p. 1190-1199 10 p.Research output: Contribution to journal › Article › peer-review
- Author Correction: Predicting Alzheimer’s disease progression using multi-modal deep learning approach (Scientific Reports, (2019), 9, 1, (1952), 10.1038/s41598-018-37769-z)Lee, G., Nho, K., Kang, B., Sohn, K. A., Kim, D., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Shaw, L. M., Khachaturian, Z., Sorensen, G., Carrillo, M., & 294 othersKuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Sather, T., Jiminez, […]
- Alzheimer’s disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individualsPettigrew, C., Nazarovs, J., Soldan, A., Singh, V., Wang, J., Hohman, T., Dumitrescu, L., Libby, J., Kunkle, B., Gross, A. L., Johnson, S., Lu, Q., Engelman, C., Masters, C. L., Maruff, P., Laws, S. M., Morris, J. C., Hassenstab, J., Cruchaga, C., Resnick, S. M., & 3 othersKitner-Triolo, M. H., An, Y. & Albert, M., Dec 2023, In: Alzheimer's Research and Therapy. 15, 1, 66.Research output: Contribution to journal › Article › peer-review
- In vivo cortical diffusion imaging relates to Alzheimer’s disease neuropathologyTorso, M., Ridgway, G. R., Valotti, M., Hardingham, I., Chance, S. A., Brewer, J., Lopez, O., Hyman, B., Grabowski, T., Sano, M., Chui, H., Albert, M., Morris, J., Kaye, J., Wisniewski, T., Small, S., Trojanowski, J., DeCarli, C., Saykin, A., Bennett, D., & 23 othersRosenberg, R., Kowall, N., Vassar, R., LaFerla, F., Petersen, R., Reiman, E., Miller, B., Levey, A., Van Eldik, L., Asthana, S., Swerdlow, R., Golde, T., Strittmatter, S., Henderson, V., Craft, S., Paulson, H., Seshadri, S., Roberson, E., Sabbagh, M., Rosenberg, G., Jefferson, A., Whitson, H. & Leverenz, […]