Morris Lab

The focus of John Morris’ research and practice is Alzheimer’s disease and other neurological disorders associated with aging. Specific research interests include improving the diagnosis of early-stage Alzheimer’s disease, clinicopathological correlations in dementing disorders, evaluating new drugs for the treatment of dementia, establishing phenotypes for inherited forms of Alzheimer’s disease and other dementias and identifying preclinical stages of Alzheimer’s disease by biomarker and neuroimaging studies.

Principal investigator

John Morris, MD

Harvey A. and Dorismae Hacker Friedman Professor of Neurology
Professor, Pathology and Immunology
Director, Section of Memory and Aging
Director, Center for Aging
Director, Memory and Aging Project
Director, Alzheimer’s Disease Research Center

• Phone: 314-286-1967

Recent publications

• Naturalistic driving measures of route selection associate with resting state networks in older adults
  December 1, 2022
  Naturalistic driving measures of route selection associate with resting state networks in older adultsWisch, J. K., Roe, C. M., Babulal, G. M., Metcalf, N., Johnson, A. M., Murphy, S., Hicks, J., Doherty, J. M., Morris, J. C. & Ances, B. M., Dec 2022, In: Scientific reports. 12, 1, 6486.Research output: Contribution to journal › Article › peer-review
• Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease
  December 1, 2022
  Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's diseaseDominantly Inherited Alzheimer Network, Dec 2022, In: Acta Neuropathologica Communications. 10, 1, 29.Research output: Contribution to journal › Article › peer-review
• Intracranial internal carotid artery calcification is not predictive of future cognitive decline
  December 1, 2022
  Intracranial internal carotid artery calcification is not predictive of future cognitive declineRahmani, F., Nguyen, M., Chen, C. D., McKay, N., Dincer, A., Joseph-Mathurin, N., Chen, G., Liu, J., Orlowski, H. L. P., Morris, J. C. & Benzinger, T. L. S., Dec 2022, In: Alzheimer's Research and Therapy. 14, 1, 32.Research output: Contribution to journal › Article › peer-review
• Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease
  August 1, 2022
  Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer diseasefor the Dominantly Inherited Alzheimer Network, Aug 1 2022, In: NeuroImage. 256, 119228.Research output: Contribution to journal › Article › peer-review
• CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer disease
  June 15, 2022
  CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer diseaseStrain, J. F., Barthelemy, N., Horie, K., Gordon, B. A., Kilgore, C., Aschenbrenner, A., Cruchaga, C., Xiong, C., Joseph-Mathurin, N., Hassenstab, J., Fagan, A. M., Li, Y., Karch, C. M., Perrin, R. J., Berman, S. B., Chhatwal, J. P., Graff-Radford, N. R., Mori, H., Levin, J., Noble, J. M., & 9 othersAllegri, R., Schofield, P. R., Marcus, D. S., Holtzman, D. M., Morris, J. C., Benzinger, T. L. S., McDade, E. M., Bateman, R. J. & Ances, B. M., Jun 15 2022, In: […]