Labs by research area
Naismith Lab
Robert T. Naismith, MD
Focused on improving care for people with multiple sclerosis through advanced imaging techniques. By using MR Diffusion Tensor Imaging to study axonal loss in the brain, spinal cord and optic nerves, the lab aims to develop clinically relevant tools that enhance diagnosis and treatment.
Neil Lab
Jeffrey J. Neil, MD, PhD
Using advanced magnetic resonance imaging and spectroscopy to study brain injury in newborns and adults. By applying techniques like diffusion tensor imaging, sodium imaging and Bayesian analysis, the lab aims to improve early detection and understanding of injury timing and progression.
Perlmutter Lab
Joel S. Perlmutter, MD
Investigating movement disorders like Parkinson’s disease and dystonia. Through neuroimaging, deep brain stimulation studies and translational research, the lab explores brain physiology, develops biomarkers and tests therapies to improve diagnosis, treatment and understanding of these conditions.
Pestronk Lab
Alan Pestronk, MD
Focused on neuromuscular disorders through clinical and research efforts. The lab investigates conditions like myopathy, neuropathy and myasthenia gravis, emphasizing neuroimmunology, aging and molecular mechanisms to improve diagnosis and treatment.
Pottier Lab
Cyril P. Pottier, PhD
Investigating genetic drivers and biomarkers of early-onset dementias, including young-onset Alzheimer’s disease and frontotemporal dementia, using multi-omics approaches to uncover therapeutic targets and modifiers.
Saligrama Lab
Naresha Saligrama, PhD
Studing adaptive immune responses in neurological health and disease. By using high-throughput sequencing and bioinformatics, the lab investigates T cell receptor diversity and antigen specificity to better understand neuroinflammatory, neurodegenerative and neuropsychiatric disorders.
Thio Lab
Kwee Liu Lin Thio, MD, PhD
Exploring cellular neurophysiology to improve understanding and treatment of pediatric epilepsy. With a focus on inhibitory glycine receptors and the ketogenic diet, the lab investigates how metabolic and molecular mechanisms influence neuronal excitability and seizure control.
Washington University Neonatal Development Research (WUNDER) Lab
Cynthia Rogers, MD & Christopher Smyser, MD
Studies how early life experiences shape brain development in infants at risk for long-term neurological challenges. Through advanced neuroimaging and clinical research, the lab aims to improve outcomes by identifying early markers of atypical development and guiding interventions.
Weihl Lab
Conrad Weihl, MD, PhD
Investigating how disruptions in protein quality control contribute to muscle and neurodegenerative diseases. Using biochemistry, cell culture, animal models and patient tissue, the lab studies conditions like inclusion body myopathy, Paget’s disease, frontotemporal dementia and limb-girdle muscular dystrophy to uncover mechanisms of protein aggregation and cellular degeneration.
Wong Lab
Michael Wong, MD, PhD
Investigating the cellular and molecular mechanisms of epilepsy and seizure-induced brain injury. Using genetic and pharmacological models, the lab focuses on tuberous sclerosis complex, acquired epilepsies and dendritic damage to uncover therapeutic targets and improve treatment strategies.