Thio Lab
Kwee Liu Lin Thio, MD, PhD
Exploring cellular neurophysiology to improve understanding and treatment of pediatric epilepsy. With a focus on inhibitory glycine receptors and the ketogenic diet, the lab investigates how metabolic and molecular mechanisms influence neuronal excitability and seizure control.
Principal investigator
Recent publications
- Delayed diagnosis in adolescent onset focal epilepsy: Impact on morbidity and mental healthHuman Epilepsy Project Investigators, Aug 2025, In: Epilepsia. 66, 8, p. 2941-2953 13 p.Research output: Contribution to journal › Article › peer-review
- Appropriate selection of participants in pediatric developmental and epileptic encephalopathy trials: Lessons learned and future opportunitiesDlugos, D., Lozano, M., DiVentura, B., Farfel, G., Shellhaas, R. A., Sullivan, J. E., Thio, L. L., Kessler, S. K., Sadleir, L. G. & French, J., Jul 2025, In: Epilepsia. 66, 7, p. e121-e126Research output: Contribution to journal › Article › peer-review
- Automated detection of interictal epileptiform discharges with few electroencephalographic channelsAlkofer, M., Yang, C., Ganglberger, W., Beal, J., Hegde, M., Kang, J. Y., Yoo, J. Y., Gelfand, M. A., Thio, L. L., Kutluay, E., Campbell, Z., Schmitt, S., Gleichgerrcht, E., Waterhouse, E., Lopez, M. R., Eisenschenk, S., Galanti, M., Singh, R. K., Wills, K. E. & Meulenbrugge, E. J. & 7 others, Dlugos, D., Dean, B., Halford, J. J., Goldenholz, D., Jing, J., Thomas, R. & Westover, M. B., Jul 2025, In: Epilepsia. 66, 7, p. e114-e120Research output: Contribution to journal › Article › peer-review
- Frequently asked questions and answers on Visually-Provoked (Photosensitive) epilepsyKasteleijn-Nolst Trenité, D., Acharya, J., Baumer, F. M., Beran, R., Craiu, D., French, J., Parisi, P., Solodar, J., Szaflarski, J. P., Takahashi, Y., Thio, L. L., Tolchin, B., Wilkins, A. & Fisher, R. S., Jun 2025, In: Epilepsy and Behavior Reports. 30, 100753.Research output: Contribution to journal › Review article › peer-review
- Comparative effectiveness of epilepsy surgery versus additional anti-seizure medications for Lennox–Gastaut syndrome: study protocol for a multicenter, mixed-methods studyLam, S., Rosenman, M., Dixon-Salazar, T., Knupp, K. G., Thio, L. L., Abel, T. J., Welch, W. P., Reed, L., Randle, S. C., Garcia-Sosa, R., Hauptman, J. S., Foster, C. C., Alpern, E. R., Zhang, L., Villalba, N., Carroll, M. & Patel, A. D., 2025, In: Frontiers in Neurology. 16, 1569551.Research output: Contribution to journal › Article › peer-review