Labs by research area
Holtzman Lab
David Holtzman, MD
Leading research into the mechanisms of neurodegeneration, with a focus on Alzheimer’s disease. Through studies on proteins like apoE and tau, and factors such as sleep, immune response and neuronal activity, the lab aims to uncover pathways that drive disease progression and identify targets for therapy.
Hyrc Lab
Krzysztof Hyrc, PhD
Studies ionic mechanisms of excitotoxic neuronal cell death. Using optical techniques and low affinity calcium indicators, the lab investigates intracellular ion concentrations to better understand how neurons respond to injury and stress.
Ju Lab
Yo-El Ju, MD, MSCI
Investigating how sleep and circadian rhythms influence neurodegenerative diseases. Through translational and clinical research, the lab aims to identify and treat sleep dysfunction to reduce disease burden, improve quality of life and promote healthy aging.
Knox Lab
Renatta Knox, MD, PhD
Focused on inherited neuromuscular disorders, including facioscapulohumeral muscular dystrophy and congenital myopathies, aiming to develop targeted therapies through molecular and translational research.
Kotzbauer Lab
Paul Kotzbauer, MD, PhD
Advances research on neurodegenerative diseases, focusing on Parkinson’s disease and infantile neuroaxonal dystrophy. The lab investigates alpha-synuclein aggregation, neuronal connectivity and enzyme dysfunction to develop imaging tools and treatments that slow disease progression and improve diagnosis.
Kress Lab
Geraldine Kress, PhD
Studing how the circadian system affects cognitive function during aging and Alzheimer’s disease. By investigating changes in brain physiology and behavior, the lab aims to uncover mechanisms that drive disease progression and identify strategies to improve outcomes and promote healthy aging.
Kummer Lab
Terrance T. Kummer, MD, PhD
Investigating cellular damage in traumatic brain injury and Alzheimer’s disease. With a focus on synaptic and gray matter injury, the lab uses innovative imaging techniques like SEQUIN to quantify synapse loss and explore its connection to neurodegeneration.
Lee Lab
Jin-Moo Lee, MD, PhD
Investigating how the brain heals after injury, focusing on stroke, Alzheimer’s disease and cerebral small vessel disease. Using molecular biology, neuroimaging and genomics, the lab bridges basic science and clinical care to develop therapies that promote recovery and repair.
Li Lab
Mingjie Li, MD, PhD
Developing viral vectors to improve gene delivery to neural cells for research and treatment of neurological disorders. Focusing on lentiviral and adeno-associated virus systems, the lab supports neuroscience studies by creating tools for cell culture and in vivo experiments that target disease mechanisms and therapeutic strategies.
Lucey Lab
Brendan P. Lucey, MD, MSCI, FAASM
Investigating how sleep affects the development and progression of Alzheimer’s disease. By studying sleep-related brain activity and biomarkers like amyloid-beta and tau, the lab aims to uncover how sleep can be used to detect, monitor and potentially prevent neurodegeneration.