Labs by research area
Saligrama Lab
Naresha Saligrama, PhD
Studing adaptive immune responses in neurological health and disease. By using high-throughput sequencing and bioinformatics, the lab investigates T cell receptor diversity and antigen specificity to better understand neuroinflammatory, neurodegenerative and neuropsychiatric disorders.
Thio Lab
Kwee Liu Lin Thio, MD, PhD
Exploring cellular neurophysiology to improve understanding and treatment of pediatric epilepsy. With a focus on inhibitory glycine receptors and the ketogenic diet, the lab investigates how metabolic and molecular mechanisms influence neuronal excitability and seizure control.
Washington University Neonatal Development Research (WUNDER) Lab
Cynthia Rogers, MD & Christopher Smyser, MD
Studies how early life experiences shape brain development in infants at risk for long-term neurological challenges. Through advanced neuroimaging and clinical research, the lab aims to improve outcomes by identifying early markers of atypical development and guiding interventions.
Weihl Lab
Conrad Weihl, MD, PhD
Investigating how disruptions in protein quality control contribute to muscle and neurodegenerative diseases. Using biochemistry, cell culture, animal models and patient tissue, the lab studies conditions like inclusion body myopathy, Paget’s disease, frontotemporal dementia and limb-girdle muscular dystrophy to uncover mechanisms of protein aggregation and cellular degeneration. [weihllab.wustl.edu]
Wong Lab
Michael Wong, MD, PhD
Investigating the cellular and molecular mechanisms of epilepsy and seizure-induced brain injury. Using genetic and pharmacological models, the lab focuses on tuberous sclerosis complex, acquired epilepsies and dendritic damage to uncover therapeutic targets and improve treatment strategies.
Wu Lab
Gregory Wu, MD, PhD
Investigates how adaptive immune responses are regulated during central nervous system inflammation. By studying monocytes, microglia and B cells in patients with multiple sclerosis and related diseases, the lab aims to uncover immune mechanisms and develop more effective therapies through clinical trials and experimental models.
Zempel Lab
John Zempel, MD, PhD
Developing advanced imaging techniques and contrast agents to improve seizure localization and damage assessment. By combining magnetic resonance imaging with electrical signal measurement, the lab enhances epilepsy diagnosis and surgical evaluation, aiming to make treatments more precise and effective.
Zhao Lab
Guoyan Zhao, PhD
Department of Genetics
Exploring transcriptional regulation in the nervous system using computational and experimental methods to understand mechanisms behind chronic pain and neurodegenerative diseases such as Alzheimer, Parkinson and Lewy body disorders.