Neurophysiology
Cirrito Lab
John Cirrito, PhD
Focuses on understanding how amyloid-beta is cleared from the brain and how this process influences Alzheimer’s disease progression. The lab uses advanced imaging, molecular biology and in vivo techniques to study synaptic activity, interstitial fluid dynamics and the role of the blood-brain barrier in amyloid clearance. Its research aims to identify therapeutic targets that can enhance clearance mechanisms and reduce neurodegeneration.
Dosenbach Lab
Nico U.F. Dosenbach, MD, PhD
Exploring the complexity of brain organization and plasticity through advanced neuroimaging and behavioral research. Using methods like precision functional mapping, brain-wide association studies and real-time MRI monitoring, the lab aims to improve understanding of individual and population-level brain function, enhance imaging quality and support therapeutic innovation.
Geisler Lab
Stefanie Geisler, MD
Investigating the molecular mechanisms behind peripheral neuropathy to develop effective treatments. Using both clinical and experimental models, the lab focuses on axon degeneration, neuron-glia interactions and chemotherapy-induced neuropathy to improve patient outcomes and quality of life.
Hyrc Lab
Krzysztof Hyrc, PhD
Studies ionic mechanisms of excitotoxic neuronal cell death. Using optical techniques and low affinity calcium indicators, the lab investigates intracellular ion concentrations to better understand how neurons respond to injury and stress.
Thio Lab
Kwee Liu Lin Thio, MD, PhD
Exploring cellular neurophysiology to improve understanding and treatment of pediatric epilepsy. With a focus on inhibitory glycine receptors and the ketogenic diet, the lab investigates how metabolic and molecular mechanisms influence neuronal excitability and seizure control.