Aging & Dementia
Balls-Berry Lab
Joyce Balls-Berry, PhD
Joyce (Joy) E. Balls-Berry, PhD, is a psychiatric epidemiologist and health educator. Her primary research focuses on applying community and patient-engaged research principles in diverse populations to reduce health disparities and increase health equity. Much of Balls-Berry’s research centers on determining ways to increase diversity and inclusion in clinical and translational science.
Bateman Lab
Randall Bateman, MD
Our laboratory’s focus is the causes, diagnosis and future treatments of Alzheimer disease. We directly measure the pathophysiology of Alzheimer disease in humans using multiple techniques and also perform in vitro cell culture experiments.
Belloy Lab
Michael Belloy, PhD
Our research is dedicated to understanding the genetics of Alzheimer’s disease and related disorders. We utilize functional genomics and bioinformatics tools to analyze publicly available cohort and population data. Our primary goal is to identify novel genetic risk variants for Alzheimer’s disease and elucidate their molecular mechanisms. This knowledge will inform drug development and advance the field of personalized genetic medicine.
Fluid Biomarker Core Lab
Anne Fagan, PhD | Suzanne E. Schindler, MD, PhD
The Fluid Biomarker Core has studied Alzheimer disease from multiple angles for more than 20 years. Currently the lab focuses on fluid biomarkers of disease with a particular interest in identifying individuals with preclinical and early stage AD. Our laboratory uses enzyme-linked immunosorbent assays (ELISA), bead-based immunoassays, single-molecule counting systems and automated immunoassays to study protein biomarkers in cerebrospinal fluid and plasma.
Research profile — Anne Fagan
Research profile — Suzanne Schindler
Gallardo Lab
Gilbert Gallardo, PhD
Understand the molecular mechanisms that regulate reactive astrocytes and their neurotoxicity in neurodegenerative diseases, including Alzheimer’s disease, by utilizing a combination of biochemistry, molecular biology, cellular models of inflammation and mouse models of neurodegenerative diseases.
Holtzman Lab
David Holtzman, MD
A major interest in the Holtzman lab is in understanding basic mechanisms underlying acute and chronic cell dysfunction in the central nervous system particularly as these mechanisms may relate to Alzheimer’s disease (AD).
Kress Lab
Geraldine Kress, PhD
My research interests focus on understanding interactions between cognitive function and the circadian system during the aging process and Alzheimer’s disease (AD) progression in order to identify pathophysiology changes, mechanisms, and possible strategies to ameliorate disease progression.
Morris Lab
John Carl Morris, MD
The focus of John Morris’ research and practice is Alzheimer’s disease and other neurological disorders associated with aging.
Musiek Lab
Erik S. Musiek, MD, PhD
The Musiek lab studies how circadian rhythms and the circadian clock system influence neurodegenerative diseases, in particular Alzheimer’s disease. Research focuses on the molecular mechanisms by which the circadian clock regulates processes such as inflammation, oxidative stress and protein aggregation in cellular and animal models of Alzhiemer’s disease and other age-related neurodegenerative conditions.
Zhao Lab
Guoyan Zhao, PhD
Department of Genetics
The Zhao lab integrates multiple cutting-edge computational and experimental approaches to study gene transcriptional regulation in the nervous system and how changes in the regulation contribute to neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson disease (PD) and Lewy body diseases (LBDs).