A recently recognized form of dementia is changing the understanding of cognitive decline, improving the ability to diagnose patients and underscoring the need for a wider array of treatments. Patients are increasingly being diagnosed with the condition, known as LATE, and guidelines advising doctors how to identify it were published this year. LATE is now estimated to […]
Nearly 7 million Americans currently live with Alzheimer’s and by 2060, experts say that number could be as high as 14 million. Scientists are trying to find out how one man has been able to stave off Alzheimer’s for 25 years, despite having a rare genetic mutation that, doctors say, essentially guaranteed he’d develop the […]
Our focus is simple: stop Alzheimer’s before it starts. This disease steals the moments that make us who we are and the memories we share. That’s why we believe in attacking Alzheimer’s from every angle — because every breakthrough means more time, more hope and more moments together for families who can’t wait.
Alzheimer’s disease is notorious for scrambling patients’ daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease. These symptoms suggest a link between the progression of the disease and the […]
Jan Kubanek, PhD, joined the faculty of WashU Medicine Department of Psychiatry on August 1, 2025, as associate professor of psychiatry in the Division of Clinical Neuroscience and Behavioral Health, with secondary appointments in the Department of Neurology and Department of Radiology. He brings combined experience in human and macaque electrophysiology, human and macaque behavioral […]
Scientists may have reached a breakthrough in the fight against Huntington’s disease, a rare and fatal inherited brain disorder with no cure. For the first time, a gene therapy has been shown in clinical trials to significantly slow the progression of the disease, raising cautious optimism among researchers and families.
Impeding a link between the body’s natural clock and the brain may help reduce neurodegeneration in mice modeling Alzheimer’s disease, according to a new study led by researchers at WashU Medicine and published in Nature Aging.
Amyotrophic lateral sclerosis (or ALS), also known as Motor Neuron Disease, is a devastating condition that gradually reduces a patient’s ability to move, speak, and ultimately breathe. Among the various forms of ALS, about 2% of cases are linked to a mutation in a gene called SOD1. For years, there has been no effective treatment […]
September 15, 2025 (Washington, DC)—The Kissick Family Foundation, in partnership with the Milken Institute Science Philanthropy Accelerator for Research and Collaboration (SPARC), today announced that the Kissick Family Foundation Frontotemporal Dementia (FTD) Grant Program has awarded four two-year grants to basic and early-stage translational research teams to advance scientific understanding of the neurodegenerative disorder. These philanthropic grants total […]