Breathing disruptions during sleep widespread in newborns with severe spina bifida (Links to an external site)

NICU baby laying on their stomach

Children with spina bifida, a malformation of the spinal cord that can lead to mobility impairments and hydrocephalus — a buildup of fluid in the brain — face significant risk of cognitive difficulties throughout their lives. A new multi-center study led by researchers at Washington University School of Medicine in St. Louis and Michigan Medicine […]

WashU startups attract record-setting $1.7 billion in private-sector investment over past year (Links to an external site)

Inside Wugen laboratory, people in white lab coats and purple gloves work at various lab stations.

Startup companies built on Washington University in St. Louis discoveries attracted a record $1.7 billion in private-sector investment over the past year, accelerating the commercialization of WashU innovations into life-changing diagnostics, therapeutics and medical devices. Among those innovations are a blood test to diagnose Alzheimer’s disease; immunotherapies to treat aggressive blood cancers; and an AI-based […]

Stimulant ADHD medications work differently than thought (Links to an external site)

Brain scan rotating to show brain areas involved in wakefulness and reward.

Prescription stimulants, such as Ritalin and Adderall, are widely used to treat attention deficit hyperactivity disorder (ADHD), including in children. In the U.S., about 3.5 million kids ages 3 to 17 take an ADHD medication, a number that has increased as more children have been diagnosed with the neurodevelopmental disorder.

New ALS drug stabilizes decline with a trend toward improved strength, mobility for some (Links to an external site)

Rickey Malloy (left), who receives tofersen treatment for SOD1-ALS at WashU Medicine, plays a round of golf with his wife, Jenny, and their son, Kash.

Historically, people with amyotrophic lateral sclerosis (ALS) experience a relentless decline of neurological function that eventually robs them of the ability to move, speak, eat or breathe. Now, researchers from Washington University School of Medicine in St. Louis and collaborators report that long-term use of tofersen, a new drug approved by the Food and Drug […]

Lee, Leuthardt awarded Falk Catalyst grant to fund acute stroke clinical trial

Headshots of Jin-Moo Lee and Eric Leuthardt

Jin-Moo Lee, MD, PhD, head of the WashU Medicine Department of Neurology, and Eric Leuthardt, MD, MBA, vice chair of innovation in the Department of Neurosurgery, have been selected as recipients of the prestigious Falk Catalyst Award. Each year, select institutions are invited to submit up to two applications to the Dr. Ralph and Marian […]