Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer’s disease. They have devised a method to study aged neurons in the lab without a brain biopsy, an advancement that could contribute to a better understanding of the disease and […]
Category: Research
Accuracy of diagnostic blood tests for Alzheimer’s disease varies (Links to an external site)
Neurologists diagnose cognitive impairment with a clinical exam of memory and thinking skills. To determine whether Alzheimer’s disease is the cause of the cognitive impairment, evidence of the specific brain changes that characterize Alzheimer’s must be obtained, typically via a brain scan or spinal tap. Identifying people whose cognitive symptoms are due to Alzheimer’s disease […]
Psilocybin generates psychedelic experience by disrupting brain network (Links to an external site)
People who consume psilocybin-containing mushrooms — otherwise known as magic mushrooms — typically undergo a surreal experience in which their sense of space, time and self is distorted. Advocates have long argued that, under the right conditions, psychedelic experiences can alleviate mental distress, and a smattering of scientific studies suggests they may be right. Understanding […]
This Is Literally Your Brain on Drugs (Links to an external site)
The image, as it happens, comes from dozens of brain scans produced by researchers at Washington University School of Medicine in St. Louis who gave psilocybin, the compound in “magic mushrooms,” to participants in a study before sending them into a functional M.R.I. scanner.
Racial disparities in dementia determined by social factors (Links to an external site)
Racial disparities in dementia are due to social determinants of health, with genetic ancestry playing no role, according to a new study led by researchers at Washington University School of Medicine in St. Louis. The study, which was based on a long-running population-based survey in four Latin American countries, helps explain why people of predominantly […]
Modifying homes for stroke survivors saves lives, extends independence (Links to an external site)
Every 40 seconds, someone in the United States suffers a stroke, in which blood flow to the brain is blocked. For the survivors, the ensuing brain damage can lead to lifelong disabilities, making mundane tasks, such as using the toilet and taking a shower, risky ventures.
Repurposed drug may help stabilize vision in rare disease (Links to an external site)
Roughly 50 families scattered across the world share ultra-rare variants in a particular gene. Silent for years, the inherited mutations make themselves known when patients reach the fourth decade of life. Changes in vision start a cascade of symptoms. Five to 20 years later, the illness is fatal.
Study aims to understand genetics of Parkinson’s disease in Black people (Links to an external site)
Erin Foster, an associate professor of occupational therapy, and Scott Norris, MD, an associate professor of neurology, have established a site at Washington University School of Medicine in St. Louis for the Black and African American Connections to Parkinson’s Disease (BLAAC PD) study, an international study aimed at understanding the gene changes that may lead to […]
Understanding role of T cells in Alzheimer’s disease is aim of new grant (Links to an external site)
There is increasing evidence that the immune system is involved in the development and progression of Alzheimer’s disease. Most research has focused on the innate immune system and its role in mediating neuroinflammation and degeneration.
‘A study to give us hope’: Lifestyle changes improve Alzheimer’s symptoms for some (Links to an external site)
Looking back, Tammy Maida, 67, said things started to change in her late 50s. At first, she would lose track of her belongings: her keys multiple times a day, a ring, eyeglasses, her purse. She would drive to the grocery store in her hometown of San Jose, California, and forget where she parked the car. […]