Historically, people with amyotrophic lateral sclerosis (ALS) experience a relentless decline of neurological function that eventually robs them of the ability to move, speak, eat or breathe. Now, researchers from Washington University School of Medicine in St. Louis and collaborators report that long-term use of tofersen, a new drug approved by the Food and Drug […]
If you need an alarm clock or other assistance to wake up, you’re probably not getting enough sleep, said Dr. Yo-El Ju, a sleep physician scientist and professor of neurology at WashU Medicine in St. Louis.
The first study to evaluate the link between Alzheimer’s disease and body weight found a significant association. Researchers at Washington University Medicine in St. Louis, Missouri, discovered that Alzheimer’s blood biomarkers increased 95% faster in people with obesity than in non-obese individuals.
T cells, also known as lymphocytes, are a type of white blood cell that play an important role in the body’s immune response. Historically, blood samples have been used to monitor how T cells respond to a virus, vaccine or immunotherapy. But a new study by researchers at Washington University School of Medicine in St. […]
Jin-Moo Lee, MD, PhD, head of the WashU Medicine Department of Neurology, and Eric Leuthardt, MD, MBA, vice chair of innovation in the Department of Neurosurgery, have been selected as recipients of the prestigious Falk Catalyst Award. Each year, select institutions are invited to submit up to two applications to the Dr. Ralph and Marian […]
A recently recognized form of dementia is changing the understanding of cognitive decline, improving the ability to diagnose patients and underscoring the need for a wider array of treatments. Patients are increasingly being diagnosed with the condition, known as LATE, and guidelines advising doctors how to identify it were published this year. LATE is now estimated to […]
Nearly 7 million Americans currently live with Alzheimer’s and by 2060, experts say that number could be as high as 14 million. Scientists are trying to find out how one man has been able to stave off Alzheimer’s for 25 years, despite having a rare genetic mutation that, doctors say, essentially guaranteed he’d develop the […]
Our focus is simple: stop Alzheimer’s before it starts. This disease steals the moments that make us who we are and the memories we share. That’s why we believe in attacking Alzheimer’s from every angle — because every breakthrough means more time, more hope and more moments together for families who can’t wait.
Alzheimer’s disease is notorious for scrambling patients’ daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease. These symptoms suggest a link between the progression of the disease and the […]
Jan Kubanek, PhD, joined the faculty of WashU Medicine Department of Psychiatry on August 1, 2025, as associate professor of psychiatry in the Division of Clinical Neuroscience and Behavioral Health, with secondary appointments in the Department of Neurology and Department of Radiology. He brings combined experience in human and macaque electrophysiology, human and macaque behavioral […]