Welders are in danger of developing symptoms similar to those of Parkinson’s disease, according to a new study that suggests exposure to fumes containing manganese makes things worse. Welding has been linked in previous research to a higher risk for parkinsonism. The term refers to a group of disorders that causes movement problems that mimic […]
Rosemary Navarro was living in Mexico when her brother called from California. Something wasn’t right with their mom, then in her early 40s. She was having trouble paying bills and keeping jobs as a food preparer in convalescent homes. Navarro, then 22, moved back to the U.S. with her two young children. Before long, Navarro […]
Like many patients visiting a doctor’s office, Kim Sebenoler started out her appointment by heading to the nearest restroom to give a urine sample. But her visit to the lab of John Constantino, MD, director of the William Greenleaf Eliot Division of Child Psychiatry, was not a typical exam. The goal was not to measure […]
In a discovery that challenges conventional thinking, researchers report that several people over the age of 90 had excellent memory even though their brains showed signs that they had Alzheimer’s disease. The meaning of the findings isn’t entirely clear. The elderly people, whose brains were studied after their deaths, may have been in the early […]
Throughout our lives, our brains are always changing. To capture that transformation, scientists will scan the brains of people from kindergarten through their later years to build maps of the brain as it develops and changes over the decades.
Scientists have linked mutations in a single gene to autism in people who have a rare tumor syndrome typically diagnosed in childhood. The findings, in patients with neurofibromatosis type 1 (NF1), may lead to a better understanding of the genetic roots of autism in the wider population.
![One February 25, 2015, Lori DeMoe McIntyre died of Alzheimer’s disease at age 56, after participating in DIAN research for nearly eight years. Her daughter Jessica McIntyre memorialized her mom with a large tattoo of Lori’s amyloid PIB PET scan. The younger McIntyre and one of her sisters participate in DIAN and DIAN-TU. [Courtesy of Jessica McIntyre, art by Joey Borger, Certified Customs, Denver, Colorado.]](https://neurology.wustl.edu/app/uploads/2022/06/image-17-300x210.png)
Part 1 of a five-part series. At age 8, DIAN has grown up. In 2008, when the Dominantly Inherited Alzheimer’s Network formally began to study autosomal-dominant AD, the notion of assembling globally dispersed families afflicted with this rare form of AD into a standing research platform seemed radical to observers. In theory, the idea of […]
Researcher is known for developing a way to measure levels of amyloid beta in brain John Cirrito, PhD, has been honored by the MetLife Foundation for his work measuring levels in the brain of amyloid beta, a protein linked to the neural degeneration of Alzheimer’s disease. John Cirrito, PhD, an associate professor of neurology at […]
Investigators will accelerate drug testing, develop new diagnostic measures. Washington University School of Medicine in St. Louis has received a $4.3 million award from the Alzheimer’s Association to expand a major international clinical trial evaluating whether drugs can prevent Alzheimer’s disease in patients genetically predisposed to develop the devastating disease at a young age. The […]
New Alzheimer’s disease research details a technique that speedily measures levels in the brain of a damaging protein fragment, and insight into why mutations in a specific gene increase the risk of developing the disease. Both studies, from researchers at Washington University School of Medicine in St. Louis, are available online in the Journal of […]