Neurodegeneration
Kotzbauer Lab
Paul Kotzbauer, MD, PhD
Advances research on neurodegenerative diseases, focusing on Parkinson’s disease and infantile neuroaxonal dystrophy. The lab investigates alpha-synuclein aggregation, neuronal connectivity and enzyme dysfunction to develop imaging tools and treatments that slow disease progression and improve diagnosis.
Kummer Lab
Terrance T. Kummer, MD, PhD
Investigating cellular damage in traumatic brain injury and Alzheimer’s disease. With a focus on synaptic and gray matter injury, the lab uses innovative imaging techniques like SEQUIN to quantify synapse loss and explore its connection to neurodegeneration.
Lee Lab
Jin-Moo Lee, MD, PhD
Investigating how the brain heals after injury, focusing on stroke, Alzheimer’s disease and cerebral small vessel disease. Using molecular biology, neuroimaging and genomics, the lab bridges basic science and clinical care to develop therapies that promote recovery and repair.
Li Lab
Mingjie Li, MD, PhD
Developing viral vectors to improve gene delivery to neural cells for research and treatment of neurological disorders. Focusing on lentiviral and adeno-associated virus systems, the lab supports neuroscience studies by creating tools for cell culture and in vivo experiments that target disease mechanisms and therapeutic strategies.
Miller Lab
Timothy Miller, MD, PhD
Focused on developing treatments for neurodegenerative diseases like ALS and dementia. Through translational neuroscience and RNA-targeted therapies, the lab investigates genetic and molecular mechanisms to create safe, effective and personalized interventions.
Morris Lab
John Carl Morris, MD
Focused on Alzheimer’s disease and age-related neurological disorders. Led by John Morris, the lab works to improve early diagnosis, explore inherited dementia phenotypes and identify preclinical stages using biomarkers and neuroimaging.
Musiek Lab
Erik S. Musiek, MD, PhD
Studies how circadian rhythms influence neurodegenerative diseases like Alzheimer’s. By examining molecular mechanisms that regulate inflammation, oxidative stress and protein aggregation, the lab aims to uncover how the circadian clock impacts brain health and identify new therapeutic targets.
Perlmutter Lab
Joel S. Perlmutter, MD
Investigating movement disorders like Parkinson’s disease and dystonia. Through neuroimaging, deep brain stimulation studies and translational research, the lab explores brain physiology, develops biomarkers and tests therapies to improve diagnosis, treatment and understanding of these conditions.
Pottier Lab
Cyril P. Pottier, PhD
Investigating genetic drivers and biomarkers of early-onset dementias, including young-onset Alzheimer’s disease and frontotemporal dementia, using multi-omics approaches to uncover therapeutic targets and modifiers.
Weihl Lab
Conrad Weihl, MD, PhD
Investigating how disruptions in protein quality control contribute to muscle and neurodegenerative diseases. Using biochemistry, cell culture, animal models and patient tissue, the lab studies conditions like inclusion body myopathy, Paget’s disease, frontotemporal dementia and limb-girdle muscular dystrophy to uncover mechanisms of protein aggregation and cellular degeneration.