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Using advanced neuroimaging to study how multiple sclerosis progresses despite treatment, aiming to uncover mechanisms of neurodegeneration and identify new therapeutic strategies.

Research profile

The Carol and Paul Hatfield Cerebral Palsy Sports & Rehabilitation Center is designed to promote the integration of young people with Cerebral Palsy and related disabilities into sports activities. CP Sports classes are supervised by physical therapists or other individuals who are trained to adapt activities to the individual participant and continuously monitor each child's progress.

The Center for Advanced Medicine is the outpatient clinic location for many of the adult specialties represented at WashU Medicine. Here patients receive multidisciplinary consultation, diagnostics, medical treatment, same-day surgery and other support services — all in one setting. This building houses the Alvin J. Siteman Cancer Center, an international leader in cancer treatment, research, prevention, education and community outreach. It is the only cancer center in Missouri and within a 240-mile radius of St. Louis to hold the Comprehensive Cancer Center designation from the National Cancer Institute and membership in the National Comprehensive Cancer Network. Siteman offers the expertise of more than 350 Washington University research scientists and physicians who provide care for more than 7,000 newly diagnosed cancer patients and more than 32,000 follow-up patients each year. These scientists and physicians currently hold nearly $150 million in cancer research and related training grants.

Delivering comprehensive, compassionate care, our program provides state-of-the-art treatment, precision medicine and holistic support for children with neuromuscular diseases. Our collaborative clinic model brings together specialists in neurology, cardiology, pulmonology, orthopedics, genetics, psychology and more — allowing families to access multiple experts in a single visit. Backed by a nationally recognized research hospital, we lead groundbreaking clinical trials and offer personalized therapies that reflect the latest innovations in pediatric neuromuscular care.

Dedicated to improving the lives of individuals with peripheral neuropathies through comprehensive clinical care and innovative research. The center integrates multidisciplinary expertise to provide advanced diagnostic evaluations, personalized treatment plans and access to clinical trials. Its mission includes fostering collaboration among clinicians and scientists, educating patients and families and developing novel therapies to address the underlying causes of neuropathy.

Advancing research on sleep and circadian rhythms as they relate to human health and disease. COBRAS facilitates collaboration among investigators across specialties, provides expertise and tools for basic, translational and clinical research, and promotes education and awareness of sleep and circadian biology. Its mission is to improve understanding of how disruptions in these systems contribute to disease and to develop strategies for prevention and treatment.

Focused on supporting every aspect of a child’s well-being, the Cerebral Palsy Center at St. Louis Children’s Hospital offers comprehensive, compassionate care for infants, children and adolescents with cerebral palsy. As part of a top-ranked pediatric hospital, our internationally recognized center provides access to leading treatments, a multidisciplinary team of specialists and unique programs like adaptive sports. Families also benefit from dedicated support services, including social work guidance and connections to community resources.

Bringing together families, caregivers and healthcare professionals, Cerebral Palsy Family Day offers a welcoming opportunity to connect, learn and engage with the latest resources and support available for individuals living with cerebral palsy. This community-focused event features educational presentations, networking opportunities and family-friendly activities designed to foster collaboration and empowerment.

Families often say the transition to adulthood with cerebral palsy is one of the hardest stages to navigate. To address this need, the Cerebral Palsy and Mobility Clinic at St. Louis Children’s Hospital developed a comprehensive online resource guide to help individuals with cerebral palsy and their families navigate adulthood.

Focuses on understanding how amyloid-beta is cleared from the brain and how this process influences Alzheimer’s disease progression. The lab uses advanced imaging, molecular biology and in vivo techniques to study synaptic activity, interstitial fluid dynamics and the role of the blood-brain barrier in amyloid clearance. Its research aims to identify therapeutic targets that can enhance clearance mechanisms and reduce neurodegeneration.

Research profile