Diringer Lab
Michael N. Diringer, MD
All neonatal intensive care unit (NNICU) physicians have specialized research interests directed at improving the care we provide our patients. A unique aspect of this facility is that it is the only Neuro-ICU in the country with a positron emission tomography (PET) scanner located on site. The PET scanner is a tool that can measure brain blood flow and metabolism which are key factors in understanding the impact of our treatments. The PET room is equipped as any other ICU room and contains all the necessary equipment needed to care for a critically ill patient. The facility is funded by grants from the National Institutes of Health.
The NNICU also supports a wide range of other clinical investigations which complement our PET studies.
Current areas of active research include
- Time course of cerebral edema formation around intracerebral hemorrhage
- Glucose metabolism following intracerebral hemorrhage
- Effect of mannitol on sodium homeostasis and osmolality
- Impact of mannitol and hypertonic saline on CBF and brain volume
- Systemic inflammatory response in subarachnoid hemorrhage
- APO-e in subarachnoid hemorrhage
- Hemodynamic augmentation in subarachnoid hemorrhage
- Impact of stains on autoregulation in acute SAH
- Use of prothrombin complex in the reversal of coumadin induced coagulopathy
Principal investigator
Michael Diringer, MD
Professor, Neurology
Professor, Neurosurgery
Associate Professor, Anesthesiology
Associate Professor, Occupational Therapy
- Phone: 314-362-2999
Recent publications
- Hemodynamic Management in the Prevention and Treatment of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid HemorrhageDeem, S., Diringer, M., Livesay, S. & Treggiari, M. M., Aug 2023, In: Neurocritical Care. 39, 1, p. 81-90 10 p.Research output: Contribution to journal › Article › peer-review
- Guidelines for the Neurocritical Care Management of Aneurysmal Subarachnoid HemorrhageTreggiari, M. M., Rabinstein, A. A., Busl, K. M., Caylor, M. M., Citerio, G., Deem, S., Diringer, M., Fox, E., Livesay, S., Sheth, K. N., Suarez, J. I. & Tjoumakaris, S., Aug 2023, In: Neurocritical Care. 39, 1, p. 1-28 28 p.Research output: Contribution to journal › Article › peer-review
- Perceived Utility of Intracranial Pressure Monitoring in Traumatic Brain Injury: A Seattle International Brain Injury Consensus Conference Consensus-Based Analysis and RecommendationsChesnut, R. M., Aguilera, S., Buki, A., Bulger, E. M., Citerio, G., Cooper, D. J., Arrastia, R. D., Diringer, M., Figaji, A., Gao, G., Geocadin, R. G., Ghajar, J., Harris, O., Hawryluk, G. W. J., Hoffer, A., Hutchinson, P., Joseph, M., Kitagawa, R., Manley, G., Mayer, S., & 21 othersMenon, D. K., Meyfroidt, G., Michael, D. B., Oddo, M., Okonkwo, D. O., Patel, M. B., Robertson, C., Rosenfeld, J. V., Rubiano, A. M., Sahuquillo, J., Servadei, F., Shutter, L., Stein, […]
- Prognostication and Goals of Care Decisions in Severe Traumatic Brain Injury: A Survey of The Seattle International Severe Traumatic Brain Injury Consensus Conference Working GroupSarigul, B., Bell, R. S., Chesnut, R., Aguilera, S., Buki, A., Citerio, G., Cooper, D. J., Diaz-Arrastia, R., Diringer, M., Figaji, A., Gao, G., Geocadin, R. G., Ghajar, J., Harris, O., Hoffer, A., Hutchinson, P., Joseph, M., Kitagawa, R., Manley, G., Mayer, S. A., & 23 othersMenon, D. K., Meyfroidt, G., Michael, D. B., Oddo, M., Okonkwo, D. O., Patel, M. B., Robertson, C., Rosenfeld, J. V., Rubiano, A. M., Sahuquillo, J., Servadei, F., Shutter, L., […]
- Computational modelling in disorders of consciousness: Closing the gap towards personalised models for restoring consciousnessLuppi, A. I., Cabral, J., Cofre, R., Mediano, P. A. M., Rosas, F. E., Qureshi, A. Y., Kuceyeski, A., Tagliazucchi, E., Raimondo, F., Deco, G., Shine, J. M., Kringelbach, M. L., Orio, P., Ching, S. N., Sanz Perl, Y., Diringer, M. N., Stevens, R. D. & Sitt, J. D., Jul 15 2023, In: NeuroImage. 275, 120162.Research output: Contribution to journal › Article › peer-review