Cell-based immunotherapy called CAR-T cell therapy has revolutionized the treatment of several cancers. The treatment uses genetically modified T cells to target and attack certain types of leukemia and lymphoma. While it can eliminate cancer in some patients who would otherwise succumb to the disease, it also comes with the risk of a range of […]
Researchers at Washington University School of Medicine in St. Louis have found a new druggable pathway that potentially could be used to help prevent Alzheimer’s dementia. Amyloid beta accumulation in the brain is the first step in the development of Alzheimer’s dementia. Scientists have poured countless hours and millions of dollars into finding ways to […]
Precision medicine, which considers the unique characteristics of individuals to provide the most effective treatment, has been a goal of health care providers for decades. Now, it is a goal for helping those with critical neurological illnesses, such as stroke, traumatic brain injury and spine trauma, to track and predict secondary injury, such as seizures, […]
A new center established at Washington University School of Medicine in St. Louis aims to accelerate research into biomarkers of neurodegenerative conditions such as Huntington’s and Parkinson’s diseases, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS) and the so-called tauopathies, a group that includes Alzheimer’s disease along with rarer diseases such as frontotemporal dementia, corticobasal syndrome […]
Alzheimer’s disease starts forming in the brains of unsuspecting individuals about 20 years before traditional telltale signs become noticeable. No cure exists for the progressive, fatal disease, but St. Louis medical researchers are studying tools and potential drugs that can detect and treat Alzheimer’s in its early stages. “The tests are getting better and better,” […]
Investigators at Washington University School of Medicine in St. Louis conduct many clinical trials and translational research studies each year to develop and evaluate new ways of treating and diagnosing myriad types of diseases. Such research holds promise for improving the health of people living in St. Louis, across the state of Missouri and around […]
Three experimental blood tests used to identify people in early stages of Alzheimer’s disease perform differently in Black individuals compared to white individuals, according to a new study from Washington University School of Medicine in St. Louis.
A new study has prompted scientists to reconsider a once-popular yet controversial idea in stroke research. Neuroscientists believed that, in the aftermath of a stroke, calming overexcited neurons might prevent them from releasing a toxic molecule that can kill neurons already damaged by lack of oxygen. This idea was supported by studies in cells and […]
People with sleep apnea wake up tired in the morning, no matter how many hours they actually sleep. The condition causes them to briefly stop and restart breathing dozens or even hundreds of times a night. Even though such breathing interruptions often don’t awaken those with apnea, they prevent them from sinking into deep, refreshing […]
Scanning the brains of newborns, researchers at Washington University School of Medicine in St. Louis have found that maternal exposure to poverty and crime can influence the structure and function of young brains even before babies make their entrances into the world. Here, the university’s Lourdes Bernardez prepares an infant for an MRI scan as […]