Adding anti-clotting drugs to stroke care ineffective, clinical trial finds (Links to an external site)

Opeolu Adeoye, MD, and Peter Panagos, MD, (right) both professors of emergency medicine at Washington University School of Medicine in St. Louis, analyze a brain scan for stroke damage. Adeoye led a national clinical trial that found that two anti-coagulant medications are ineffective at improving post-treatment outcomes for stroke patients. (Photo: Tim Miller)

Stroke patients who survive a blood clot in the brain’s blood vessels are prone to developing new blockages during their recovery periods, even if they receive vessel-clearing interventions. In an effort to avoid further clots, doctors at 57 sites around the U.S. tested a possible solution: the addition of anti-coagulant drugs to medicine that dissolves […]

Multiple sclerosis appears to protect against Alzheimer’s disease (Links to an external site)

A collaborative investigation among WashU Medicine experts in Alzheimer’s disease and multiple sclerosis (MS) finds evidence that MS patients are less likely to have amyloid plaques, a hallmark of Alzheimer's disease, than adults without MS.

People with multiple sclerosis (MS) are far less likely than those without the condition to have the molecular hallmarks of Alzheimer’s disease, according to new research from Washington University School of Medicine in St. Louis. The discovery suggests a new avenue of research through which to seek Alzheimer’s treatments, said Matthew Brier, MD, PhD, an assistant […]

58 Neurology faculty recognized as 2024 Castle Connolly Top Doctors®

Neurology Top Doctors 2024

The Department of Neurology is pleased to announce 58 of our faculty members have been selected as 2024 Castle Connolly Top Doctors®. We are proud of our physicians for their dedication to their work and patients each and every day. Each year, Castle Connolly uses a merit-based system to select board-certified physicians for its Top […]

First-ever WashU ALS Symposium brings national ALS community together

Individuals with amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, their caregivers, friends, family and medical providers who specialize in ALS treatment and research had the opportunity to connect at the first-ever Washington University ALS Symposium Saturday, Aug. 3, 2024. The event, hosted by the Washington University Department of Neurology ALS Center, was held at […]

Blood tests for Alzheimer’s may be coming to your doctor’s office. Here’s what to know (Links to an external site)

FILE - A doctor points to PET scan results that are part of a study on Alzheimer’s disease at Georgetown University Hospital, on Tuesday, May 19, 2015, in Washington. (AP Photo/Evan Vucci, File)

New blood tests could help doctors diagnose Alzheimer’s disease faster and more accurately, researchers reported Sunday – but some appear to work far better than others. It’s tricky to tell if memory problems are caused by Alzheimer’s. That requires confirming one of the disease’s hallmark signs — buildup of a sticky protein called beta-amyloid — with a hard-to-get brain […]

Three Washington University child neurologists distinguished in first-ever Child Neurology Society fellow class

2024 Fellow of the Child Neurology Society Christopher Smyser Soe Mar Renee Shellhaas

Christopher Smyser, MD, MSCI, Soe Mar, MD, MBBS, MRCP, and Renée Shellhaas, MD, MS, have all been included in the inaugural Fellow of the Child Neurology Society (FCNS) program class. The designation “recognizes and honors our dedicated members’ professional achievements and contributions.” In order to be eligible, the applicant must be an active member in good standing with […]

Staff spotlight Lori Nichols

Lori Nichols

Lori Nichols is a native of Collinsville, Illinois. She earned Bachelor of Arts degrees in both Psychology and Sociology as well as a Master of Science in Education from Southern Illinois University in Carbondale. Following graduate school, she returned to the St. Louis area and now calls Crestwood, Missouri home.  She began her career in […]

Aging-related genomic culprit found in Alzheimer’s disease (Links to an external site)

Researchers at Washington University School of Medicine in St. Louis have developed a way to study aged neurons in the lab without a brain biopsy, allowing them to accurately model the effects of aging in the development of late-onset Alzheimer's disease. Shown is a 3D reconstruction of amyloid beta plaque deposition (green) between neurons (red) grown in the lab. These neurons were transformed from human skin cells taken from patients with late-onset Alzheimer's disease.

Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer’s disease. They have devised a method to study aged neurons in the lab without a brain biopsy, an advancement that could contribute to a better understanding of the disease and […]

Accuracy of diagnostic blood tests for Alzheimer’s disease varies (Links to an external site)

A head-to-head comparison of six commercially available blood tests for Alzheimer’s disease led by researchers at Washington University School of Medicine in St. Louis reveals that two are accurate enough to replace brain scans and spinal taps in some patients with cognitive impairments.

Neurologists diagnose cognitive impairment with a clinical exam of memory and thinking skills. To determine whether Alzheimer’s disease is the cause of the cognitive impairment, evidence of the specific brain changes that characterize Alzheimer’s must be obtained, typically via a brain scan or spinal tap. Identifying people whose cognitive symptoms are due to Alzheimer’s disease […]

Faculty spotlight Mai Dang

Mai Dang

Mai Dang, MD, PhD, started her formal education in the small town of Janesville, Wisconsin. She and her ethnic Chinese family landed there after they immigrated to the U.S. from Vietnam. They then moved to Chicago when she was in middle school. She attended the University of Chicago for college and majored in sociology with […]