Research

Antibody removes Alzheimer’s plaques, in mice

Washington University School of Medicine in St. Louis •
Antibodies against APOE (red) bind to amyloid plaques (blue) in brain tissue from people with Alzheimer's disease. Researchers have found that the antibody can sweep away the damaging plaques, at least in mice, which could lead to a therapy for the devastating disease.
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Years before people start showing characteristic symptoms of Alzheimer’s disease, sticky plaques begin forming in their brains, damaging nearby cells. For decades, doctors have sought ways to clear out these plaques as a way to prevent or treat the disease.