$35 million to support study of sleep disorder linked to neurodegeneration

A study participant wears monitoring equipment as part of a sleep study on REM sleep behavior disorder. Researchers at Washington University School of Medicine in St. Louis, Mayo Clinic in Rochester, Minn., and The Neuro (Montreal Neurological Institute-Hospital) of McGill University have received a five-year grant expected to total $35.1 million for an extension of a study designed to develop biomarkers that indicate which people with the sleep disorder will go on to develop neurodegenerative diseases.
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People with rapid eye movement (REM) sleep behavior disorder act out their dreams. While sleeping safely in bed, for example, they might throw up their arms to catch an imaginary ball or try to run from an illusory assailant. Such actions are more than just a nuisance. People with the disorder have a 50% to 80% chance of developing a serious neurodegenerative disease within a decade of diagnosis.