Research

Mice sleeping fitfully provide clues to insomnia

Researchers at Washington University School of Medicine in St. Louis – working with mice with sleep problems similar to those experienced by people with the genetic disease neurofibromatosis type 1 (NF1) – believe the animals will help shed light on insomnia linked to NF1 or other factors.
View Content

Mice that sleep fitfully could help researchers unravel the mystery of insomnia.

Researchers at Washington University School of Medicine in St. Louis studied mice genetically modified to mimic the genetic disease neurofibromatosis type 1 (NF1), which is associated with sleep problems. They found that the animals, like some people with NF1, slept in short, irregular spurts. Studying these mice could help identify the molecular and cellular mechanisms that go awry and cause fragmented sleep patterns in people with and without the disease, the researchers said.