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Intellectual and Developmental Disabilities Research Center (IDDRC)

Fostering innovation in neurodevelopmental research

Promoting research aimed at understanding and treating neurodevelopmental disorders. The center provides core facilities, collaborative opportunities and educational programs to support investigators studying the biological, genetic and behavioral aspects of intellectual and developmental disabilities. Its mission is to accelerate discoveries that improve diagnosis, intervention and outcomes for individuals affected by these conditions.

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John L. Trotter Multiple Sclerosis Center

A leading provider of comprehensive care and expertise

Center provides comprehensive care for individuals with multiple sclerosis and related disorders while advancing research to improve treatment and outcomes. The center offers personalized care plans, access to clinical trials and multidisciplinary expertise in neurology, rehabilitation and symptom management. Its mission includes fostering collaboration, educating patients and families and developing innovative therapies through cutting-edge research.

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Knight ADRC Clinical Trials Unit

Accelerating research and equity in Alzheimer’s treatment

Leading global efforts to develop and test promising therapies for Alzheimer’s disease and related dementias. In collaboration with the Global Alzheimer’s Platform Foundation and over 100 research partners, the unit conducts clinical trials aimed at reducing disease progression, improving patient outcomes and increasing diversity in research participation. With more than 35 years of experience and over 5,400 participants, the center is committed to advancing science and ensuring equitable access to innovative treatments.

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Knight Alzheimer Disease Research Center

Advancing research to prevent and treat Alzheimer’s disease

Committed to improving diagnosis, care and prevention of Alzheimer’s disease through cutting-edge research and education. The center supports scientists, clinicians and the public by fostering collaboration and providing resources for studies on clinical, genetic and neuropathological aspects of Alzheimer’s and related disorders. Its long-term goal is to develop effective treatments and preventive strategies for dementia.

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Moyamoya Center

Conducting long-term research on the natural history of patients with Moyamoya disease and their outcome after surgery

Offers comprehensive evaluation and treatment for patients with moyamoya disease and related cerebrovascular conditions. The center combines advanced diagnostic imaging, surgical expertise and multidisciplinary care to improve patient outcomes. In addition to clinical services, it conducts research to better understand moyamoya pathophysiology and develop innovative therapies, while providing education for patients and healthcare professionals.

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Neurofibromatosis Center

Providing exceptional care through groundbreaking research

Dedicated to improving the lives of individuals with neurofibromatosis (NF) through comprehensive clinical care and innovative research. The center integrates multidisciplinary expertise to provide personalized treatment plans, genetic counseling and access to clinical trials. Its research initiatives focus on understanding the biology of NF, developing targeted therapies and promoting education for patients, families and healthcare professionals

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Rett Spectrum Clinic

Providing specialized care and research for Rett syndrome and related disorders

A collaboration between WashU Medicine and St. Louis Children’s Hospital, the clinic brings together specialists in neurology, genetics and rehabilitation to provide personalized care plans, genetic counseling and access to clinical trials. Its mission includes improving quality of life through multidisciplinary care, advancing research on Rett syndrome and educating families and healthcare professionals.

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RVCL Research Center

Advancing discovery and treatment for RVCL

Dedicated to understanding and treating retinal vasculopathy with cerebral leukoencephalopathy (RVCL), a rare genetic disorder that affects small blood vessels in the brain, eyes and other organs. The center combines clinical care, genetic counseling and cutting-edge research to uncover disease mechanisms and develop targeted therapies. Its mission includes fostering collaboration among scientists, educating patients and families and accelerating progress toward effective treatments.

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Tracy Family SILQ Center

Accelerating biomarker discovery for neurodegenerative diseases

Advancing research on Alzheimer’s disease and other neurodegenerative disorders by utilizing mass spectrometry and innovative labeling techniques. Its mission is to identify and validate biomarkers for diagnosis and prognosis, understand protein aggregation in disease processes and accelerate the development of effective treatments. The center fosters collaboration among scientists and supports pilot studies to generate data for sustainable research initiatives.

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Tuberous Sclerosis Center

Comprehensive care and groundbreaking research for all ages

Offering comprehensive care for individuals with tuberous sclerosis complex (TSC) while advancing research to improve treatment and outcomes. The center brings together experts in neurology, genetics and related specialties to deliver personalized care plans, genetic counseling and access to clinical trials. Its mission includes fostering collaboration, educating patients and families and developing innovative therapies through cutting-edge research.