Research Centers

Committed to advancing understanding of Parkinson’s disease and related movement disorders through cutting-edge research and collaborative initiatives. The center integrates basic science, translational studies and clinical trials to uncover disease mechanisms and develop novel therapies. Its mission includes fostering partnerships among scientists and clinicians, promoting education and improving patient care through evidence-based approaches.

A multi-site research initiative funded by the National Institutes of Health that investigates how brain connectivity changes with age and what factors contribute to cognitive resilience or decline. Building on the Human Connectome Project in Aging, AABC follows over 1,000 adults aged 36 and older using brain imaging, cognitive testing, surveys and biospecimen collection. The study emphasizes diversity in its participant pool and examines influences such as stress, lifestyle, sleep and hormonal changes to identify pathways that promote healthy brain aging.

Provides high-quality, compassionate care for individuals diagnosed with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, while advancing research to develop new therapies. Its multidisciplinary team integrates clinical care, clinical trials and translational research to improve understanding of ALS and accelerate treatment development. The center emphasizes collaboration among physicians, clinicians and scientists to offer personalized care and pursue innovative approaches aimed at finding effective therapies and ultimately a cure.

Providing specialized rodent surgical services to support neuroscience and translational research. With over 50 years of experience, the core offers custom procedures, project planning assistance and guidance through Institutional Animal Care and Use Committee (IACUC) approval. It serves as a resource for investigators by offering expertise in neurological models, access to funding opportunities and a wide range of surgical techniques designed to enhance research quality and efficiency.

Dedicated to improving the lives of individuals with peripheral neuropathies through comprehensive clinical care and innovative research. The center integrates multidisciplinary expertise to provide advanced diagnostic evaluations, personalized treatment plans and access to clinical trials. Its mission includes fostering collaboration among clinicians and scientists, educating patients and families and developing novel therapies to address the underlying causes of neuropathy.

Advancing research on sleep and circadian rhythms as they relate to human health and disease. COBRAS facilitates collaboration among investigators across specialties, provides expertise and tools for basic, translational and clinical research, and promotes education and awareness of sleep and circadian biology. Its mission is to improve understanding of how disruptions in these systems contribute to disease and to develop strategies for prevention and treatment.

An international research initiative focused on understanding and preventing dominantly inherited Alzheimer’s disease (DIAD). DIAN conducts long-term observational studies and clinical trials to identify biomarkers, track disease progression and evaluate potential therapies. Through its trials unit (DIAN-TU), the program leads pioneering prevention studies targeting individuals with genetic mutations linked to early-onset Alzheimer’s. DIAN also supports families through genetic counseling, education and opportunities to participate in research that may benefit future generations

A leading resource for Alzheimer’s disease research, offering one of the world’s largest biorepositories of blood and cerebrospinal fluid samples. The lab specializes in fluid biomarker assays for analytes such as Aβ42, Aβ40, tau, p-tau181, NfL and GFAP, supporting studies on disease diagnosis, prognosis and therapeutic response. Operating under Good Clinical Practice guidelines, the lab collaborates internationally to standardize and validate biomarker measures, aiming to translate research findings into clinical care.

Dedicated to improving lives through interdisciplinary research focused on neurodegeneration and neural repair. By fostering collaboration among scientists, the center promotes innovative approaches to understanding brain disorders and translating discoveries into treatments. Its resources include specialized research groups, core facilities and educational programs designed to accelerate breakthroughs in neurological health.

Offering comprehensive care for individuals affected by Huntington’s disease and related disorders while advancing research to improve diagnosis and treatment. The center brings together specialists in neurology, genetics and psychiatry to deliver personalized care plans, genetic counseling and access to clinical trials. Its mission includes fostering collaboration, educating patients and families and developing innovative therapies through cutting-edge research.