Yo-El Ju, MD, MSCI
The Ju lab studies the relationship between sleep and neurodegenerative diseases through translational and clinical research.
Eric Landsness, MD, PhD
Stroke occurs due to a loss of blood flow to the brain, resulting in significant brain injury and disability. Currently, over 7 million people in the United States suffer from the long-term effects of stroke and is the third leading cause of death in the United States. Recovery from stroke requires plasticity to allow remapping, or “rewiring,” of disrupted neuronal circuits. Such mechanisms are influenced by sleep, which is an ideal target for therapeutic intervention due to its well-studied role in mediating plasticity. Our lab studies the connection between plasticity-dependent mechanisms for stroke recovery and sleep-dependent plasticity. Our goal is to develop new, innovative sleep-focused treatments and interventions to improve outcomes in patients with neurological disease.
Brendan P. Lucey, MD, MSCI, FAASM
The Lucey lab investigates the relationship between sleep, aging and Alzheimer’s disease. Recent evidence suggests a role for sleep in Alzheimer’s disease pathogenesis and/or as a marker for the onset and/or progression of Alzheimer’s disease that could be followed as an outcome measure in treatment trials. The major goal of our research is use sleep to prevent or delay Alzheimer’s disease.