Multiple Sclerosis & Neuroimmunology
Brier Lab
Matthew R. Brier, MD, PhD
Using advanced neuroimaging to study how multiple sclerosis progresses despite treatment, aiming to uncover mechanisms of neurodegeneration and identify new therapeutic strategies.
Cross Lab
Anne Cross, MD
Investigating the immunological processes underlying multiple sclerosis and related neuroinflammatory disorders. The lab focuses on understanding how immune cells interact with the central nervous system, identifying biomarkers of disease activity and developing strategies to prevent or reverse neurodegeneration. Its research integrates clinical observations with experimental models to advance therapeutic approaches and improve patient outcomes.
Li Lab
Mingjie Li, MD, PhD
Developing viral vectors to improve gene delivery to neural cells for research and treatment of neurological disorders. Focusing on lentiviral and adeno-associated virus systems, the lab supports neuroscience studies by creating tools for cell culture and in vivo experiments that target disease mechanisms and therapeutic strategies.
Naismith Lab
Robert T. Naismith, MD
Focused on improving care for people with multiple sclerosis through advanced imaging techniques. By using MR Diffusion Tensor Imaging to study axonal loss in the brain, spinal cord and optic nerves, the lab aims to develop clinically relevant tools that enhance diagnosis and treatment.
Saligrama Lab
Naresha Saligrama, PhD
Studing adaptive immune responses in neurological health and disease. By using high-throughput sequencing and bioinformatics, the lab investigates T cell receptor diversity and antigen specificity to better understand neuroinflammatory, neurodegenerative and neuropsychiatric disorders.
Wu Lab
Gregory Wu, MD, PhD
Investigates how adaptive immune responses are regulated during central nervous system inflammation. By studying monocytes, microglia and B cells in patients with multiple sclerosis and related diseases, the lab aims to uncover immune mechanisms and develop more effective therapies through clinical trials and experimental models.