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Hope Center for Neurological Disorders

Advancing collaborative research for brain health

Dedicated to improving lives through interdisciplinary research focused on neurodegeneration and neural repair. By fostering collaboration among scientists, the center promotes innovative approaches to understanding brain disorders and translating discoveries into treatments. Its resources include specialized research groups, core facilities and educational programs designed to accelerate breakthroughs in neurological health.

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Huntington’s Disease Center of Excellence

Adult

Offering comprehensive care for individuals affected by Huntington’s disease and related disorders while advancing research to improve diagnosis and treatment. The center brings together specialists in neurology, genetics and psychiatry to deliver personalized care plans, genetic counseling and access to clinical trials. Its mission includes fostering collaboration, educating patients and families and developing innovative therapies through cutting-edge research.

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Intellectual and Developmental Disabilities Research Center (IDDRC)

Fostering innovation in neurodevelopmental research

Promoting research aimed at understanding and treating neurodevelopmental disorders. The center provides core facilities, collaborative opportunities and educational programs to support investigators studying the biological, genetic and behavioral aspects of intellectual and developmental disabilities. Its mission is to accelerate discoveries that improve diagnosis, intervention and outcomes for individuals affected by these conditions.

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John L. Trotter Multiple Sclerosis Center

A leading provider of comprehensive care and expertise

Center provides comprehensive care for individuals with multiple sclerosis and related disorders while advancing research to improve treatment and outcomes. The center offers personalized care plans, access to clinical trials and multidisciplinary expertise in neurology, rehabilitation and symptom management. Its mission includes fostering collaboration, educating patients and families and developing innovative therapies through cutting-edge research.

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John L. Trotter Multiple Sclerosis Center

Adult

Recognized for excellence in MS care, our center delivers comprehensive, patient-focused services backed by decades of clinical experience. Leveraging advanced diagnostics and collaborative expertise, our fellowship-trained physicians provide accurate evaluations and personalized treatment plans. As a National MS Society Center for Comprehensive Care, we offer access to cutting-edge clinical trials and work closely with subspecialists across the Washington University Medical Campus to ensure every patient receives the right care — even if MS is not the final diagnosis.

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Ju Lab

Yo-El Ju, MD, MSCI

Investigating how sleep and circadian rhythms influence neurodegenerative diseases. Through translational and clinical research, the lab aims to identify and treat sleep dysfunction to reduce disease burden, improve quality of life and promote healthy aging.

Research profile

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June Jessee Memorial Foundation

The June Jessee Memorial Foundation (JJMF) is a nonprofit organization that provides relief and support to help children with devastating medically complex, neurological conditions and their families in the St. Louis area and beyond.

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Kang Lab

Peter Kang, MD, MSCI

Advancing a wide spectrum of neurovascular research, the Kang Lab studies small vessel disease, cerebral blood flow and metabolism, ischemic vulnerability and neuroinflammation, while also examining how critical illness shapes cognitive decline and improving neurocritical care through clinical trials, outcomes research, quality initiatives and education.

Research profile

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Knight ADRC Clinical Trials Unit

Accelerating research and equity in Alzheimer’s treatment

Leading global efforts to develop and test promising therapies for Alzheimer’s disease and related dementias. In collaboration with the Global Alzheimer’s Platform Foundation and over 100 research partners, the unit conducts clinical trials aimed at reducing disease progression, improving patient outcomes and increasing diversity in research participation. With more than 35 years of experience and over 5,400 participants, the center is committed to advancing science and ensuring equitable access to innovative treatments.

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Knight Alzheimer Disease Research Center

Advancing research to prevent and treat Alzheimer’s disease

Committed to improving diagnosis, care and prevention of Alzheimer’s disease through cutting-edge research and education. The center supports scientists, clinicians and the public by fostering collaboration and providing resources for studies on clinical, genetic and neuropathological aspects of Alzheimer’s and related disorders. Its long-term goal is to develop effective treatments and preventive strategies for dementia.