Cognitive function in Down syndrome-associated Alzheimer’s focus of grant

Nearly every person with Down syndrome eventually develops Alzheimer’s disease, yet people with the syndrome routinely are excluded from Alzheimer’s clinical trials, as the cognitive assessment tools designed for the general population often are inappropriate for people with developmental disabilities. Consequently, nobody knows whether the new Alzheimer’s therapeutics hitting the market will work for people with Down syndrome. This puts this population at risk of missing out on potentially life-changing therapies.