The new generation of Alzheimer’s disease drugs — the first proven to change the course of the disease — typically extend independent living for patients by 10 months. Called monoclonal antibodies, they reduce the accumulations of a harmful protein, amyloid, in the brain and require high-dose, once- or twice-monthly infusions of the medication.
A new case report published by David B. Clifford, MD, and colleagues detailed the anti-amyloid therapy treatment course of a patient who developed Alzheimer’s disease concurrently with a pre-existing HIV diagnosis. The patient, who was diagnosed with HIV in 2005, began showing signs of cognitive decline in 2015 and received a clinical diagnosis of Alzheimer’s […]
Older adults who experienced at least one fall exhibited a faster decline in cognitive skills over the following decade than those who hadn’t fallen, according to a new study by researchers at Washington University School of Public Health in St. Louis. The study also revealed that falls are a risk factor for Alzheimer’s disease on […]
Scientists showed in a new study published Thursday that they could use blood draws to build a “clock” for Alzheimer’s disease that could roughly predict whensymptoms will develop, findings that could eventually transform how the illness is diagnosed and treated.
Researchers at Washington University School of Medicine in St. Louis have developed a method to predict when someone is likely to develop symptoms of Alzheimer’s disease using a single blood test. In a new study published Feb. 19 in Nature Medicine, the researchers demonstrated that their models predicted the onset of Alzheimer’s symptoms within a […]
Acute provoked neonatal seizures (also known as acute symptomatic neonatal seizures) can occur in newborns whose brains are injured by a range of causes from stroke and bleeding in the brain to central nervous system infections. While the seizures themselves are scary enough for the families, the story continues after the neonates are treated for […]
A single blood test may be able to predict when a person will develop Alzheimer’s symptoms—years before memory loss begins—according to new research from the Washington University School of Medicine in St Louis. According to the researchers, their concept could estimate the age of onset of Alzheimer’s symptoms to within three to four years—an ability that could transform both […]
The Department of Neurology at WashU Medicine is proud to announce that it has been ranked No. 2 in NIH funding among all neurology departments across the U.S. This prestigious ranking reflects the exceptional dedication and groundbreaking work of our faculty, staff and trainees. Department leadership would like to extend their heartfelt gratitude to all […]
Chimeric antigen receptor (CAR) T cell therapy, a type of immunotherapy that leverages the immune system to combat diseases, is a powerful treatment option for certain cancers. The treatment relies on genetically modified T cells — a type of immune cell — to destroy cancer cells.
Parkinson’s disease, a progressive neurological disorder affecting more than 1 million people in the U.S. and more than 10 million globally, is characterized by debilitating symptoms such as tremors, movement difficulties, sleep disturbances and cognitive impairments. While current treatments, including long-term medication and invasive deep brain stimulation (DBS), can alleviate symptoms, they cannot halt progression […]