Section of Aging & Dementia

Director

Chief

Faculty

Patient care

Memory Diagnostic Center

Research

Recent publications

• Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes
  January 9, 2025
  Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomesGuo, J. L., Braun, D., Fitzgerald, G. A., Hsieh, Y. T., Rougé, L., Litvinchuk, A., Steffek, M., Propson, N. E., Heffner, C. M., Discenza, C., Han, S. J., Rana, A., Skuja, L. L., Lin, B. Q., Sun, E. W., Davis, S. S., Balasundar, S., Becerra, I., Dugas, J. C. & Ha, C. & 22 others, Hsiao-Nakamoto, J., Huang, F., Jain, S., Kung, J. E., Liau, N. P. D., Mahon, C. S., Nguyen, H. N., Nguyen, N., Samaddar, M., Shi, Y., Tatarakis, D., Tian, Y., Zhu, […]
• Unlocking Cognitive Analysis Potential in Alzheimer's Disease Clinical Trials: Investigating Hierarchical Linear Models for Analyzing Novel Measurement Burst Design Data
  December 30, 2024
  Unlocking Cognitive Analysis Potential in Alzheimer's Disease Clinical Trials: Investigating Hierarchical Linear Models for Analyzing Novel Measurement Burst Design DataWang, G., Hassenstab, J., Li, Y., Aschenbrenner, A. J., McDade, E. M., Llibre-Guerra, J., Bateman, R. J. & Xiong, C., Dec 30 2024, In: Statistics in medicine. 43, 30, p. 5898-5910 13 p.Research output: Contribution to journal › Article › peer-review
• Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
  December 4, 2024
  Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy modelCarling, G. K., Fan, L., Foxe, N. R., Norman, K., Wong, M. Y., Zhu, D., Corona, C., Razzoli, A., Yu, F., Yarahmady, A., Ye, P., Chen, H., Huang, Y., Amin, S., Sereda, R., Lopez-Lee, C., Zacharioudakis, E., Chen, X., Xu, J. & Cheng, F. & 10 others, Gavathiotis, E., Cuervo, A. M., Holtzman, D. M., Mok, S. A., Sinha, S. C., Sidoli, S., Ratan, R. R., Luo, W., Gong, S. & Gan, L., Dec 4 2024, In: Neuron. 112, 23, p. 3877-3896.e8Research output: Contribution to journal › […]
• Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s disease
  December 1, 2024
  Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s diseaseDominantly Inherited Alzheimer Network, Dec 2024, In: Nature communications. 15, 1, 9982.Research output: Contribution to journal › Article › peer-review
• Gaps in biomedical research in frontotemporal dementia: A call for diversity and disparities focused research
  December 1, 2024
  Gaps in biomedical research in frontotemporal dementia: A call for diversity and disparities focused researchISTAART Frontotemporal Dementia and Related Disorders PIA, ISTAART Diversity and Disparities PIA, Dec 2024, In: Alzheimer's and Dementia. 20, 12, p. 9014-9036 23 p.Research output: Contribution to journal › Article › peer-review