Mice sleeping fitfully provide clues to insomnia (Links to an external site)

Researchers at Washington University School of Medicine in St. Louis – working with mice with sleep problems similar to those experienced by people with the genetic disease neurofibromatosis type 1 (NF1) – believe the animals will help shed light on insomnia linked to NF1 or other factors.

Mice that sleep fitfully could help researchers unravel the mystery of insomnia. Researchers at Washington University School of Medicine in St. Louis studied mice genetically modified to mimic the genetic disease neurofibromatosis type 1 (NF1), which is associated with sleep problems. They found that the animals, like some people with NF1, slept in short, irregular […]

Alzheimer’s Disease May Develop Differently In African-Americans, Study Suggests (Links to an external site)

A colorized image of a brain cell from an Alzheimer's patient shows a neurofibrillary tangle (red) inside the cytoplasm (yellow) of the cell. The tangles consist primarily of a protein called tau.

Scientists have found a biological clue that could help explain why African-Americans appear to be more vulnerable than white Americans to Alzheimer’s disease. A study of 1,255 people, both black and white, found that cerebrospinal fluid from African-Americans tended to contain lower levels of a substance associated with Alzheimer’s, researchers report Monday in the journal JAMA Neurology.

Racial differences in Alzheimer’s disease unveiled (Links to an external site)

A new study at Washington University School of Medicine in St. Louis finds disparities between African-Americans and Caucasians in a key biomarker for Alzheimer’s disease – suggesting that tools to diagnose the disease in Caucasian populations may not work as well in African-Americans.

African-Americans may be twice as likely as Caucasian Americans to develop Alzheimer’s disease, but nobody knows why because studies investigating the underlying causes of illness have historically drawn from a nearly all-white pool of research participants. Consequently, little is known about how the neurodegenerative disease arises and progresses in people of non-Caucasian backgrounds.

People who act out dreams needed for study (Links to an external site)

Acting out dreams can be an early sign of serious neurological disease. A new study aims to identify which people with the disorder will go on to develop neurodegenerative diseases such as Parkinson’s, and to lay the groundwork to test treatments aimed at preventing such diseases.

Picture this: A soccer referee, dreaming he’s on the pitch, flings his arm up with an imaginary red card and accidentally smacks his sleeping partner in the face. Funny? Maybe on TV. In real life, acting out dreams is not only bad for domestic harmony, it can be a warning sign of looming neurodegenerative disease.

Medical students honor their teachers at ceremony (Links to an external site)

Several of those honored with 2017-18 Distinguished Service Teaching Awards celebrate at the awards ceremony Nov. 15 at the Eric P. Newman Education Center on the Medical Campus.

Washington University School of Medicine students recently honored faculty and residents with Distinguished Service Teaching Awards for the 2017-18 academic year. The awards, which were first given in 1991, reflect the students’ appreciation for dedication, patience and skill in training aspiring physicians.

Scoliosis linked to essential mineral (Links to an external site)

An inability to properly use the essential mineral manganese could be to blame for some cases of severe scoliosis, according to a new study from Washington University School of Medicine in St. Louis.

Nobody knows why some children’s backs start to curve to one side just as they hit puberty. Most children diagnosed with scoliosis, or curvature of the spine, have no known risk factors.

Gurnett named director of pediatric and developmental neurology (Links to an external site)

Christina Gurnett, MD, PhD, an expert in epilepsy and neurodevelopmental disorders, has been named director of the Division of Pediatric and Developmental Neurology at the School of Medicine and neurologist-in-chief at St. Louis Children's Hospital.

Christina Gurnett, MD, PhD, a professor of neurology at Washington University School of Medicine in St. Louis, has been named director of the Division of Pediatric and Developmental Neurology at the School of Medicine and neurologist-in-chief at St. Louis Children’s Hospital.