Morris Lab
John Carl Morris, MD
The focus of John Morris’ research and practice is Alzheimer’s disease and other neurological disorders associated with aging. Specific research interests include improving the diagnosis of early-stage Alzheimer’s disease, clinicopathological correlations in dementing disorders, evaluating new drugs for the treatment of dementia, establishing phenotypes for inherited forms of Alzheimer’s disease and other dementias and identifying preclinical stages of Alzheimer’s disease by biomarker and neuroimaging studies.
Principal investigator
John Morris, MD
Harvey A. & Dorismae Hacker Friedman Professor of Neurology
Director, Section of Aging & Dementia
Professor, Pathology and Immunology
Director, Center for Aging
Director, Memory and Aging Project
- Phone: 314-286-1967
Top areas of adult care: Alzheimer’s disease, dementia, geriatric neurology
Recent publications
- Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohortOka, T., Matsuzawa, Y., Tsuneyoshi, M., Nakamura, Y., Aoshima, K., Tsugawa, H., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Shaw, L. M., Liu, E. & Montine, T. & 278 others, Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Donohue, M., Bernstein, M., Fox, N., Thompson, P., Schuff, N., DeCArli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., […]
- Baseline levels and longitudinal changes in plasma Aβ42/40 among Black and white individualsXiong, C., Luo, J., Wolk, D. A., Shaw, L. M., Roberson, E. D., Murchison, C. F., Henson, R. L., Benzinger, T. L. S., Bui, Q., Agboola, F., Grant, E., Gremminger, E. N., Moulder, K. L., Geldmacher, D. S., Clay, O. J., Babulal, G., Cruchaga, C., Holtzman, D. M., Bateman, R. J. & Morris, J. C. & 1 others, Schindler, S. E., Dec 2024, In: Nature communications. 15, 1, 5539.Research output: Contribution to journal › Article › peer-review
- Gene-SGAN: discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clusteringYang, Z., Wen, J., Abdulkadir, A., Cui, Y., Erus, G., Mamourian, E., Melhem, R., Srinivasan, D., Govindarajan, S. T., Chen, J., Habes, M., Masters, C. L., Maruff, P., Fripp, J., Ferrucci, L., Albert, M. S., Johnson, S. C., Morris, J. C., LaMontagne, P. & Marcus, D. S. & 8 others, Benzinger, T. L. S., Wolk, D. A., Shen, L., Bao, J., Resnick, S. M., Shou, H., Nasrallah, I. M. & Davatzikos, C., Dec 2024, In: Nature communications. 15, 1, 354.Research output: Contribution to journal › Article › […]
- Genetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research CenterFernandez, M. V., Liu, M., Beric, A., Johnson, M., Cetin, A., Patel, M., Budde, J., Kohlfeld, P., Bergmann, K., Lowery, J., Flynn, A., Brock, W., Sanchez Montejo, B., Gentsch, J., Sykora, N., Norton, J., Gentsch, J., Valdez, O., Gorijala, P. & Sanford, J. & 24 others, Sun, Y., Wang, C., Western, D., Timsina, J., Mangetti Goncalves, T., Do, A. N., Sung, Y. J., Zhao, G., Morris, J. C., Moulder, K., Holtzman, D. M., Bateman, R. J., Karch, C., Hassenstab, J., Xiong, C., Schindler, S. […]
- Characteristics of discordance between amyloid positron emission tomography and plasma amyloid-β 42/40 positivityPyun, J. M., Park, Y. H., Youn, Y. C., Kang, M. J., Shim, K. H., Jang, J. W., You, J., Nho, K., Kim, S. Y., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J. & Morris, J. & 63 others, Shaw, L. M., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Hendrix, J., Vasanthakumar, […]