Kress Lab
Geraldine Kress, PhD
My research focuses on understanding how cognitive function interacts with the circadian system during aging and the progression of Alzheimer’s disease (AD). The goal is to:
- Identify changes in pathophysiology
- Uncover underlying mechanisms
- Explore strategies to slow or mitigate disease progression
This work aims to advance our understanding of neurodegenerative processes and inform the development of targeted interventions.
Principal investigator
Our team
Recent publications
- Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neuronsCarrillo-Reid, L., Day, M., Xie, Z., Melendez, A. E., Kondapalli, J., Plotkin, J. L., Wokosin, D. L., Chen, Y., Kress, G. J., Kaplitt, M., Ilijic, E., Guzman, J. N., Chan, C. S. & Surmeier, D. J., Apr 2019, In: eLife. 8, e40818.Research output: Contribution to journal › Article › peer-review
- Regulation of amyloid-β dynamics and pathology by the circadian clockKress, G. J., Liao, F., Dimitry, J., Cedeno, M. R., FitzGerald, G. A., Holtzman, D. M. & Musiek, E. S., Apr 1 2018, In: Journal of Experimental Medicine. 215, 4, p. 1059-1068 10 p.Research output: Contribution to journal › Article › peer-review
- Fast phasic release properties of dopamine studied with a channel biosensorKress, G. J., Shu, H. J., Yu, A., Taylor, A., Benz, A., Harmon, S. & Mennerick, S., Aug 27 2014, In: Journal of Neuroscience. 34, 35, p. 11792-11802 11 p.Research output: Contribution to journal › Article › peer-review
- Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's diseasePlotkin, J. L., Day, M., Peterson, J. D., Xie, Z., Kress, G. J., Rafalovich, I., Kondapalli, J., Gertler, T. S., Flajolet, M., Greengard, P., Stavarache, M., Kaplitt, M. G., Rosinski, J., Chan, C. S. & Surmeier, D. J., Jul 2 2014, In: Neuron. 83, 1, p. 178-188 11 p.Research output: Contribution to journal › Article › peer-review
- Convergent cortical innervation of striatal projection neuronsKress, G. J., Yamawaki, N., Wokosin, D. L., Wickersham, I. R., Shepherd, G. M. G. & Surmeier, D. J., Jun 2013, In: Nature neuroscience. 16, 6, p. 665-667 3 p.Research output: Contribution to journal › Article › peer-review
- Optical approaches to studying the basal gangliaPlotkin, J. L., Guzman, J. N., Schwarz, N., Kress, G., Wokosin, D. L. & Surmeier, D. J., 2011, Animal Models of Movement Disorders: Volume I. Lane, E. & Dunnett, S. (eds.). p. 191-220 30 p. (Neuromethods; vol. 61).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
- Axonal sodium channel distribution shapes the depolarized action potential threshold of dentate granule neuronsKress, G. J., Dowling, M. J., Eisenman, L. N. & Mennerick, S., Apr 2010, In: Hippocampus. 20, 4, p. 558-571 14 p.Research output: Contribution to journal › Article › peer-review
- Action potential initiation and propagation: Upstream influences on neurotransmissionKress, G. J. & Mennerick, S., Jan 12 2009, In: Neuroscience. 158, 1, p. 211-222 12 p.Research output: Contribution to journal › Review article › peer-review
- High threshold, proximal initiation, and slow conduction velocity of action potentials in dentate granule neuron mossy fibersKress, G. J., Dowling, M. J., Meeks, J. P. & Mennerick, S., Jul 2008, In: Journal of neurophysiology. 100, 1, p. 281-291 11 p.Research output: Contribution to journal › Article › peer-review
- Anticonvulsant and anesthetic effects of a fluorescent neurosteroid analog activated by visible lightEisenman, L. N., Shu, H. J., Akk, G., Wang, C., Manion, B. D., Kress, G. J., Evers, A. S., Steinbach, J. H., Covey, D. F., Zorumski, C. F. & Mennerick, S., Apr 2007, In: Nature neuroscience. 10, 4, p. 523-530 8 p.Research output: Contribution to journal › Article › peer-review