An idea that has propelled Alzheimer’s research for more than 30 years is approaching its day of reckoning. Scientists are launching a study designed to make or break the hypothesis that Alzheimer’s is caused by a sticky substance called beta-amyloid. The study will give an experimental anti-amyloid drug to people as young as 18 who […]
Families that have a child with Rett syndrome, a rare neurological disorder that almost exclusively affects females, often travel hundreds of miles to the Rett Spectrum Clinic in St. Louis — a collaboration between Washington University School of Medicine and St. Louis Children’s Hospital — for multispecialty care and access to innovative clinical trials.
Scientists have identified a handful of gene mutations that cause or contribute to the onset of Alzheimer’s disease. But many scientists suspect that other DNA changes may help drive Alzheimer’s-related damage to brain cells and lead to symptoms of confusion and memory loss experienced by patients.
When the COVID-19 pandemic struck in the spring of 2022, students and staff at schools that serve children with intellectual and developmental disabilities (IDD) were left stranded. These students and staff faced unique circumstances because they could not always follow the CDC guidance on masking, testing, and social distancing due to the nature of these […]
Using demographic information, brain imaging test results and genetic biomarkers, researchers at Washington University School of Medicine in St. Louis have developed an algorithm that can help provide people who volunteer for studies of aging with information about the risk each faces of developing dementia due to Alzheimer’s disease.
If you’ve had COVID-19, it may still be messing with your brain. Those who have been infected with the virus are at increased risk of developing a range of neurological conditions in the first year after the infection, new research shows. Such complications include strokes, cognitive and memory problems, depression, anxiety and migraine headaches, according […]
An investigational drug developed to treat a rare, inherited form of amyotrophic lateral sclerosis (ALS) reduced molecular signs of the fatal, paralyzing disease and curbed neurodegeneration — but at the six-month mark, the drug did not improve motor control and muscle strength, according to results from a phase 3 clinical trial led by researchers at […]
Cell-based immunotherapy called CAR-T cell therapy has revolutionized the treatment of several cancers. The treatment uses genetically modified T cells to target and attack certain types of leukemia and lymphoma. While it can eliminate cancer in some patients who would otherwise succumb to the disease, it also comes with the risk of a range of […]
Researchers at Washington University School of Medicine in St. Louis have found a new druggable pathway that potentially could be used to help prevent Alzheimer’s dementia. Amyloid beta accumulation in the brain is the first step in the development of Alzheimer’s dementia. Scientists have poured countless hours and millions of dollars into finding ways to […]
Precision medicine, which considers the unique characteristics of individuals to provide the most effective treatment, has been a goal of health care providers for decades. Now, it is a goal for helping those with critical neurological illnesses, such as stroke, traumatic brain injury and spine trauma, to track and predict secondary injury, such as seizures, […]