International Alzheimer’s prevention trial in young adults begins (Links to an external site)

Primary Prevention trial participant Hannah Richardson, 24, undergoes a clinical exam given by WashU Medicine neurologist Nupur Ghoshal, MD, PhD. The international trial, led by WashU Medicine, aims to determine whether stopping the early molecular changes that lead to symptomatic Alzheimer’s disease can prevent the disease from ever taking hold.

The first participants in an international clinical trial aimed at preventing Alzheimer’s disease in young adults at high risk of the disease have been enrolled. The trial, led by Washington University School of Medicine in St. Louis, aims to determine whether stopping the early molecular changes that lead to symptomatic Alzheimer’s disease can prevent the […]

Foster to be inducted into AOTA’s Roster of Fellows (Links to an external site)

Congratulations to Erin Foster, PhD, OTD, OTR/L who will receive the American Occupational Therapy Association’s (AOTA’s) Roster of Fellows Award at AOTA’s Inspire 2025 Annual Conference & Expo in Philadelphia, Pa. The Roster of Fellows recognizes occupational therapists who through their knowledge, expertise, leadership, advocacy, and/or guidance have made a significant contribution over time to […]

Lauber, Mallmann and Musser announced as Neurology Staff Employees of the Quarter

Lauber, Mallmann and Musser

The Department of Neurology congratulates three staff members for being awarded the Neurology Staff Employees of the Quarter for Q2 FY25. The department accepts nominations for three award categories to highlight the dedication and accomplishments of our staff members — clinical, research and administration. Clinical Staff Employee of the Quarter Joanne Lauber Clinical Nurse CoordinatorSection […]

Brains of people with sickle cell disease appear older (Links to an external site)

A new study led by WashU Medicine researchers has found older-looking brains in adults with sickle cell disease, helping to explain the cognitive challenges experienced by such individuals. A brain image from a healthy individual (left) shows a larger brain with more white matter compared with a brain image from a patient with sickle cell disease (right). Healthy individuals experiencing economic deprivation also had more-aged appearing brains.

Individuals with sickle cell disease – a chronic illness where misshapen, sticky blood cells clump together, reducing oxygen delivery to organs – are at a higher risk for stroke and resulting cognitive disability. But even in the absence of stroke, many such patients struggle with remembering, focusing, learning and problem solving, among other cognitive problems, […]

New Qalsody Results Bring Hope for Recovery of Lost Function and More Time (Links to an external site)

For decades, the general consensus among neurologists and neuroscientists has been that ALS treatments would only be able to slow down or stop further progression of the disease. Function that had already been lost would probably not be recovered. But now, evidence is emerging that not only is functional improvement possible, it’s happening for some people […]

Fatal neurodegenerative disease in kids also affects the bowel (Links to an external site)

Researchers at WashU Medicine have described the neurodegeneration that occurs in the nervous system of the bowel in Batten disease, a rare and fatal genetic condition. In their latest study, a team led by Jonathan Cooper, professor of pediatrics (left), showed that gene therapy to the bowel in mice modeling Batten disease reduced symptoms and extended lifespan. Also pictured are co-first authors Ewa Ziółkowska (center), a postdoctoral research associate, and Matt Jansen, a graduate student. (Photo: Matt Miller/WashU Medicine)

As a leading researcher of rare diseases that affect children’s brains, Jonathan D. Cooper, PhD, thought little about the gastrointestinal (GI) system. That is, until the parents of children with a condition that Cooper studies urged him to investigate why debilitating digestive issues troubled their kids, who suffer from an incurable and fatal neurodegenerative brain condition […]

Could inhaling xenon gas help treat Alzheimer’s? A new mouse study suggests it might (Links to an external site)

A medical device used for xenon therapy. Adobe

The gas xenon, like the other noble, or inert, gases, is known for doing very little. The class of elements, because of its molecular structure, don’t typically interact with many chemicals.  But a new mouse study shows one possible use case for xenon — as a treatment for Alzheimer’s disease. The paper, published Wednesday in Science Translational […]

Neurology, I2DB announce joint faculty hire

The Department of Neurology and the Institute for Informatics, Data Science and Biostatistics (I2DB) are pleased to welcome a new joint faculty member, Laura Wiley, PhD, FAMIA, who is serving as an associate professor as of Jan. 1. She will also serve as the Director of Clinical Data Science in the Office of the Chief […]

2025-2026 Academic Year Neurology Residency Program Chief Residents

The Department of Neurology is pleased to announce our Neurology Residency Program chief residents for the 2025-2026 academic year. This group of remarkable individuals will be working with their resident colleagues, staff, faculty and leadership to continue strengthening our program as a leader in neurology residency training. Thank you to our current chief residents, Drs. […]