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UID:20250214T1602Z-1739548941.8651-EO-10998-1@10.73.10.224
STATUS:CONFIRMED
DTSTAMP:20260715T205723Z
CREATED:20250214T153954Z
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DTSTART;TZID=America/Chicago:20250221T120000
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SUMMARY: COBRAS Speaker Series | Maria Gonzalez-Aponte
DESCRIPTION: COBRAS Seminar Series “Clock Hijackers: Circadian signaling in
  glioblastoma synchronizes tumor daily rhythms and regulates tumor progress
 ion” Glioblastoma (GBM) is a deadly brain tumor that\, unlike other cancers
 \, sustains intrinsic circadian rhythms in clock gene expression that synch
 ronize to the host. We now find that daily glucocorticoid receptor signalin
 g acts as an intrinsic driver of […]
X-ALT-DESC;FMTTYPE=text/html: <p>COBRAS Seminar Series</p><p><em>“Clock Hij
 ackers: Circadian signaling in glioblastoma synchronizes tumor daily rhythm
 s and regulates tumor progression”</em></p><p>Glioblastoma (GBM) is a deadl
 y brain tumor that\, unlike other cancers\, sustains intrinsic circadian rh
 ythms in clock gene expression that synchronize to the host. We now find th
 at daily glucocorticoid receptor signaling acts as an intrinsic driver of G
 BM progression and a synchronizer of tumor clock gene expression to the hos
 t. This work provides an intrinsic circadian driver\, and therapeutic targe
 t\, to slow GBM growth\, and offers considerations for glucocorticoid use i
 n the clinic.</p><p>Dr. Maria Felicita Gonzalez-Aponte<br />Postdoctoral Re
 search Associate (Herzog Lab)<br />Arts & Sciences\, Department of Biology<
 br />Washington University in St. Louis</p><p>Join us in person in Holden A
 uditorium<br />Zoom: <a href="https://wustl-hipaa.zoom.us/j/95243853618">ht
 tps://wustl-hipaa.zoom.us/j/95243853618</a></p><p>Friday\, February 21\, 20
 25<br />Noon – 1:00 pm<br />Holden Auditorium\, FLTC<br />1-hour CME availa
 ble for this lecture</p>
CATEGORIES:COBRAS
LOCATION:Holden Auditorium\, FLTC
GEO:38.636879;-90.262646
ORGANIZER;CN="Katie Cammarata":MAILTO:cammarata@wustl.edu
URL;VALUE=URI:https://neurology.wustl.edu/events/event/cobras-speaker-serie
 s-maria-gonzalez-aponte/
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DTSTART:20241103T070000
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